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《Chinese Journal of Biotechnology》 1993-01
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A Feasibility Study of Multivariable Self-tuning Control for Biochemical Processes——Fed-Batch Penicillin Fermentation

Ye Kaiming, Jin Sha, Zhang Siliang, Yu Juntang (Research Institute of Biochemical Engineering, East China University of Chemical Technology, Shanghai 200237)  
A second-order discrete MIMO (Mult Input Mult Output) model matching the industrial data is presented in this paper, With this model system identification and MIMO adaptive control of fed-batch penicillin fermentation is studied by means of one set of computer on-line sampling and measuring system. It is shown that the process can be controlled to a reference optimization trajectory by adaptive control law, This MIMO adaptive controller for fed-batch penicillin fermentation is more simple and easy to be put into operation.
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