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Studies on the Callus Culture of Ginkgo biloba and its Metabolites ginkgolides

Yu Rongmin Zhao Honglian Zheng Yuguo Yao Xinsheng Zhang Hui (Shenyang Pharmaceutical University, Shenyang 110015)  
The production of Ginkgolides in callus culture of Ginkgo biloba was reported. The affection of some physical factors and chemical substances on the induction and growth of calli was also investigated. A biologically quantitative method (platelet aggregation induced by PAF) and HPLC were successfully used for the determination of Ginkgolides A and B in all kinds of callus cultures. The result showed that the content of Ginkgolide B in the callus cultures varies from 0.005% to 0.01%, which is one of the best result for the callus culture of G.biloba in the world.
【Fund】: 辽宁省自然科学基金
【CateGory Index】: Q944.6
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