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《CHINESE JOURNAL OF BIOTECHNOLOGY》 1999-01
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Expression of Nephroblastoma Proto oncogene nov C Induced by tTA Regulation SystemThis experiment has got the fund by Chinese Academy of Science for studing abroad.It is made part of the wokes in the Lab.of tumour virology and molecular biology inst

Luo Yishan 1 Xiong Kejuan 1 C.Martlnerle 2 B.Perbal 3 1 (Wuhan institute of Virology,CAS,Wuhan,430071) 2(Institute Curie,CNRS,France ORSAY,91405,UFR de) 3(Biochemi Universitaire de Parie 7-D,France)  
nov gene is a related gene with Nephroblastoma,over expressed in all Nephroblastoma tested,but its expression was not detectable in normal adult kindeys.In this paper,Bujard's tTA regulation system had been established in QT6 cell line successfully,and novC was expressed at high levels induced by this system,the molecular weight of expressed Nov protein is 48 kD,so,one cell line over expressed the nov had been established in vitro.This is necessary for the study of the regulation principle of nov gene in the cell.
【Fund】: 中国科学院留学基金
【CateGory Index】: R730.23
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