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《Shanghai Medical Journal》 1992-01
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INVESTIGATION OF HUMAN CYTOMEGALOVIRUS INFECTION OF CHILDBEARING AGE WOMEN, PREGNANT WOMEN AND THEIR INFANTS

Xu Gui-lin, et al. Department of Microbiology, Shanghai Second Medical University, Shanghai 200025  
In order to investigate the situation of human cytomegalovirus (HCMV) infection in Shanghai, we have detected the HCMV specific antibody in 1048 serum samples of child- bearing age women and 289 paired serum samples of mother and infant by indirect ELISA. The positive rate of HCMV-IgG of childbearing age women was 93.5%. The positive rates of HCMV-IgG in18, 20-29 and 30-45 years of age were 54.9%, 89.7% and 95.5% respectively. It suggests that the HCMV infection increases with age. In addition, we also found that HCMV infection is related to the status of socioeconomy and marriage. Two hundred seventy-three maternal serum samples and 266 umbilical cord serum samples were positive for HCMV-IgG, with positive rates of 94.46% and 92.04% respectively. While 13 maternal serum samples and 10 umbilical cord serum samples were positive for HCMV-IgM, with positive rates of 4.49% and 3.46% respectively. The close relation of HCMV-IgM levels between mothers and their babies indicated that infants might acquire congenital infection from their mothers with positive HCMV-IgM.
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【References】
Chinese Journal Full-text Database 3 Hits
1 Lun Yu-lan, Research Institute for Family Planning, Qingdao, 266071;Morphological Observation on Chorionic Tissue after Cvtomegalovirus Infection.[J];Chinese Journal of Family Planning;1993-04
2 CUI Yingqi DONG Zhaowen LUN Yulan~* HAN Weitian~(**) WANG Yi CHEN Lu~* QU Ou~(**) National Research Institute for Family Planning,Beijing 100081 ~*Qingdao Family Planning Institute ~(**)Liaoning Family Planning Institute;Investigation of active human cytomegalovirus infection of 1 202 early pregnant women[J];Journal fo Reproductive Medicine;1993-04
3 LU Jia-liang, WANG Yun-fei, LIU Pei-li. Department of Epidemiology, Shcool of Public Health, Fudan University (Shanghai 200032, China);Study on Risk Factors of HCMV Reactivate Infection in Pregnancy and Influence on Fetus[J];China Public Health;2002-04
【Co-references】
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1 Shao Jijun, et al Department of Microbiology;PRELIMINARY STUDIES ON THE RELATIONSHIP BETWEEN CONJENITALCYTOMEGALOVIRUS INFECTION AND INFANTILE MALFORMATION[J];;1988-02
2 Wang Shufeng Ma Jingya Zhang Libi (Insiituie of Virology, Chinese Academy of Preventive Medicine, Beijing);SURVEY OF URINE SPECIMENS FROM KINTER-GARDEN CHILDREN IN BEIJING FOR CYT-OMEGALOVIRUS INFECTION BY DNA-DNA HYBRIDIZATION METHOD[J];Chinese Journal of Virology;1988-01
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【Secondary References】
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1 Xie Xinbao,Zhu Qirong,Wang Xiaohong,et al.Children , s Hospital,Fudan University,Shanghai 200032,China;Analysis of 328 children with elevated aminotransferase levels.[J];Chinese Journal of Practical Pediatrics;2005-11
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