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Expression and Significance of P_(53)、bcl-2 and Ki-67 Proteins in Human Medulloblastomas

FU Xin ge, LI Feng, HU Wen hao, TAO Lin, LI Hong an, Jiang Jin fang, Chen Yun zhao, Chen Hua\;(Cancer Research Center and Department of Pathology,Medical College, Shihezi University, Shihezi 832002, China)  
The expressions of Ki 67?P\-\{53\} and bcl 2 proteins were studied immunohistochemically by S P method in 25 cases of medulloblastoma. The results showed that the positive rates of bcl 2 and P\-\{53\} proteins was 72% and 16% in 25 cases of medulloblastoma respectively.The index of Ki 67 was (33.34±4.98)%, and its expression was correlated with histological type. This study indicated that the bcl 2 and P\-\{53\} probably took part in controlling cell apoptosis in medulloblastoma.
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