Müller Cells and Retinal Function
YANG XiongLi (Shanghai Institute of Physiology, Chinese Academy of Sciences, Shanghai 200031)
Müller cells are the principal neuroglia cells in the retina. Recently, a lot of evidence indicate that there exist twoway communications between Müller cells and retinal neurons. Müller cells may modulate neuronal activity in the retina either indirectly through modifying neuronal microenvironment or directly by controlling the concentration of neuroactive substances in extracellular space, in addition to their general supporting and nourishing roles. Müller cells thereby play an important role in retinal function.