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Research progress in epigenetics alterations by occupational hazards

XV Xiao-wen;XIA Zhao-lin;Department of Occupational Health and Toxicology,School of Public Health,Fudan University;Key Laboratory of Public Health and Safety of Ministry of Education of China;  
Long-term exposure to occupational hazards may severely threaten the health of workers,leading to multi-systemic damages. Genetics mechanism has been proved to be an important mechanism of the damage caused by occupational hazards,epigenetic alterations are the principal pathway of pathogenesis as well. This article will give a brief introduction of the epigenetic changes caused by occupational hazards,discuss the role of epigenetic alterations in the development of environmental diseases,thereby provide some effective prevention and control measures.
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