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《MEDICAL JOURNAL OF QILU》 1998-01
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OBSERVATION OF CELL IMMUNE FUNCTION IN PATIENTS WITH MIDDLE AND LATE STAGE MALIGNANT TUMOR

Kao Jun, Lou Jian' gang, Wang Yanqiu, et al. No. 2 People's hospital Qingdao, Qingdao 266033 [  
Objective To observe the changes of erythrocyte immune function, T lymphocyte subpopulation and solubte interleukin-2 receptor levels in malignant tumor patient. Methods The changes of erythrocyte immune function, T lymphoryte subpopulation and soluble interleukin-2 receptor levels were measured in 66 patients wich unresectable malignant tumor and 36 healthy people by erythrocyte receptor rosette test, alkaline phosphatase anti- alkaline phusphatase and ELISA methods. Results The erythrocyte C3b receptor rosette rate (E-C3bRR), CD4, CD4 /CD8 were signifcantly lower, the erythrotyte inmmune complex rosette rate, CD8, slL-2R were sigaificantly higher in patients with malignant tumor than that in normal controls ( t= 5. 363-131, 524, P0. 001). There were positive correlations between E-C3bRR and CD4, CD4/CD8(r=0. 409-0. 527, P 0. 001), slL-2R and CD8(r=0. 384, P0. 001), negetive correletions between E-C3bRR and CD8, slL-2R and CD4 ,CD4/CD8 (r=-0. 450--0. 530,P0. 001). Conclusion There are obvious abnormalities in erythrocyte immune function,T lympho- cytes subpopulation and slL-2R in patients with unresectable malignant tumor. [
【CateGory Index】: R730.3
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