Solid phase extraction of food contaminants using molecular imprinted polymers

ZHANG Xing-yue,YU Hai-peng,LIU Jun-hong(College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,China)  

Food contamination from natural or anthropogenic sources poses severe risks to human health.It is now largely accepted that continuous exposure to low doses of toxic chemicals can be related to several chronic diseases,including some type of cancer and serious hormonal dysfunctions.Contemporary analytical methods have the sensitivity required for contamination detection and quantification,but direct application of these methods on food samples can be rarely performed.Current sample pre-treatment methods,mostly based on the solid phase extraction technique,are very fast and inexpensive but show a lack of selectivity,while methods based on immunoaffinity extraction are very selective but expensive.Recent years have seen a significant increase of the "molecularly imprinted solid phase extraction"(MISPE)technique in the food contaminant analysis.In this review,several applications of MISPE in food contamination analysis were discussed,with particular emphasis on the extraction of pesticides,drugs residua,mycotoxins and environmental contaminants.

【Key Words】： molecular imprinting solid phase extraction food analysis contaminants pesticides mycotoxins
【CateGory Index】： TS207.5

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