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《Food Science》 2009-05
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Study on Hypoglycemic Function of Polysaccharides from Lycium ruthenicum Murr. Fruit and Its Mechanism

WANG Jian-hong,CHEN Xiao-qin,ZHANG Wei-jiao (College of Life Science and Chemistry, Xinjiang Normal University, Urumuqi 830054, China)  
In this study, two ways was used to prove and explain the hypoglycemic function of polysaccharides from Lycium ruthenicum Murr. fruit, among which, one way was to preventively administer the normal mice by gavage with the low, middle or high dosages of the polysaccharides for 11 d, and then intraperitoneally inject the prevented mice with alloxan, and another way was to intraperitoneally inject the normal mice with alloxan to establish diabetic models, and then intraperitoneally administer the diabetic mice by gavage with the low, middle or high dosages of the polysaecharides for 21 d. Finally the hepatin in liver, SOD activity and MDA content in serum and liver, and fasting blood glucose level were determined for the control group, diabetic model group, all treatment groups and metformin hydrochloride group. The results showed that the polysaccharides signifi- cantly can reduce glucose level in blood and MDA content in blood and liver, and enhance SOD activity in blood and liver and promote conversion of blood glucose into liver glycogen of diabetic mice. In conclusion, the polysaccharides from Lycium ruthenicum Murr. fruit has prevention and therapeutic effects on hyperglycemia, and can effectively enhance the anti-oxidation ability in diabetic mice induced by alloxan.
【Fund】: 新疆维吾尔自治区自然科学基金项目(20032111);; 新疆师范大学博士科研启动基金项目
【CateGory Index】: R285.5
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【Citations】
Chinese Journal Full-text Database 8 Hits
1 Li Buqing;Zhang Huiling;Shu Qingling;Zhang Buchang;Ge Shengfang(Institute of Green Food Engineering,Anhui Academy of Agricultural Sciences,Hefei 230031);Studies on the Extraction of Polysaccharide From Middle and Lower Middle Grade Green Tea and the Effectiveness on Blood-glucose Depressing[J];JOURNAL OF TEA SCIENCE;1996-01
2 XI Jin-biao 1,2,4, ZHANG Fu-suo 1,2, MAO Da-ru2, YAN Ping3(1.Xinjiang Ecological and Geographical Institute, Chinese Academy of Science, Xinjiang 830011,China; 2.Key Laboratory of Plant Nutrition, MOA; Key Laboratory of Plant-Soil Interactions, MOE; Department of Plant Nutrition, China Agricultural University, Beijing 100094,China; 3.Shihezi University, Shihezi 832003,China;4.Shandong Academy of Forestry Science, Jinan 250014,China);The Utilization of Halophytes for Traditional Medicine in Xinjiang[J];Review of China Agricultural Science and Technology;2003-01
3 Can Qingmei, Luo Guifa, Li Puyan Zhuoma Dongzhu, Chen Yuerong, Zuo Zhenchang (Qinghai Provincial Institute for Drug Control 810000);THE STUDY OF TIBETAN DRUG LYCIUM RUTHENICIUM MURR IN DEVELOPMENT AND UTILIZATION[J];Qinghai Science and Technology;1997-01
4 LI Jin1,2,QU Wei-jing1,* (1.Life Science Institute, East China Normal University, Shanghai 200062, China; 2.Life and Environment Science Institute, Xinjiang Normal University, Uruquqi 830054, China);Study on Adsorption and Desorption of the Pigments of Lycium ruthenicum Murr.with Macroporous Resin[J];Food Science;2005-06
5 Chen Hongjun 1 Bai Hongjin 1 Wang Xiaoming 1 Kong Xinyun 2 (1,Dept of Public course,Tarim University of Agrivultural Reclamation,Alar Xingjiang 843300) (2,Tarim University of Agrivultural Reclamation,Alar Xingjiang 843300);Study on Extracting Method of Red Pigment in Lycium Ruthenicum Murray[J];JOURNAL OF TARIM UNIVERSITY OF AGRICULTURAL RECLAMATION;2000-02
6 LI Jin 1, ZHU Changqin 1, YUAN Hui 1, HAN Bin 1, SHI Dehong 2 (1.School of Life and Environment Sciences,Xinjiang Normal University Uruquqi,830054,China; 2.The Second Middle School of Chang Ji,Changji Xinjiang 831100,China);A Study on The Extracting Technology of Pigments of Lycium ruthenicum Murr[J];Journal of Xingjiang Normal University(Natural Sciences Edition);2005-01
7 GAN Qing mei (Qinghai Institute for Drug Control, Xining Qinghai 810000, China);Preliminary investigation on Tibetan Medicinal Herb[J];Chinese Traditional and Herbal Drugs;2001-04
8 Lin Dingyun;Li Wei(Jiangsu Academy of Agricultural Science Nanjing,210014)Gan Qingmen;Zuo Zhenchang(Qinghai Institute of Drug Examination);Preliminary Studies on Pigment in Fruits of Lycium Ruthenicum Murr.[J];CHINA FOOD ADDITIVES;1995-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Zhou Hanru (Department of Biology);Observation on Anatomical Structure of Leaves or Assimilating Branches of Five Solonchalk Plants in Xinjang[J];Journal of Anhui University(Natural Sciences);1991-04
2 MO Hai-zhen et al (Department of Food Science,Henan Institute of Science and Technology,Xinxiang,Henan 453003);Technology of Lactic Acid Fermented Cactus Jelly[J];Journal of Anhui Agricultural Sciences;2006-15
3 LI Gang et al (Hanan Institute of Science and Technology,Xinxiang,Henan 453003);Research on the Preparation of Soybean Oligasaccharide Extracted from Defatted Soybean[J];Journal of Anhui Agricultural Sciences;2006-15
4 DU Qing-dong(Life Science College,Linyi Normal College,Linyi,Shandong 276005);Development and Utilization of Healthy Food of Chinese Yam Bean[J];Journal of Anhui Agricultural Sciences;2006-17
5 TU Er-xun et al (Key Laboratory of Tarim Animal Husbandry Science & Technology,Xinjiang Production & Construction Group,Alar,Xinjiang 843300);Study on the Extracting Technology of Pigment of Lycium ruthenicum Murr[J];Journal of Anhui Agricultural Sciences;2007-04
6 SUN Mu-fang et al(Xinyang Agricultural College,Xinyang,Henan 464000);Optimization of Extraction Technology for Tea Polysaccharides of Xinyangmaojian with Microwave Technique[J];Journal of Anhui Agricultural Sciences;2007-17
7 SUN Mu-fang et al (Xinyang Agricultural College, Xinyang, Henan 464000);Research Status and Prospect of Purification Technique for Tea Polysaccharides Compound[J];Journal of Anhui Agricultural Sciences;2007-26
8 YUAN Xiao-qing et al(State Key Laboratory of Food Science and Technology,Southern Yangtze University,Wuxi,Jiangsu 214122);Separation and Purification of a Water Soluble Hypoglycemic Polypeptide MC2-1-5 from Momordica charantia L. Var. abbreviata Ser[J];Journal of Anhui Agricultural Sciences;2007-31
9 HAN Zhi-ping et al (College of Chemistry and Chemical Engineering,Yulin College,Yulin,Shaanxi 719000);Analysis and Evaluation on Nutritive Composition of Chinese Dates in Different Producing Areas of North Shaanxi[J];Journal of Anhui Agricultural Sciences;2007-31
10 WANG Xiao-ling (College of Life Science and Technology,Central South University of Forestry &Technology,Changsha,Hunan 410004);Present Situation and Development Countermeasures of Ecological Agriculture and Green Food in China[J];Journal of Anhui Agricultural Sciences;2007-34
China Proceedings of conference Full-text Database 7 Hits
1 XIONG Zheng-ying LI Feng (Shanxi Normal University,Xipan,710062,China);The Influence of Algae Supplement on Sports Ability[A];[C];2007
2 LIU Nan LU Xiao-ling YAO Xiu-ling(Tianjin University of Science and Technology,Tianjin 300457);The extraction and research of pigment from black carrot[A];[C];2007
3 Wang Min Wang Weimin Chen Suhua (Guangdong Ocean University,Zhanjiang 524025,China);The immunoregulatory effect of the flavonoids of mango peels[A];Chinese Society of Agricultural Engineering[C];2007
4 Li Jianrong (College of Food Science, Biotechnology & Environment Engineering, Zhejiang Gongshang University, HangZhou 310035);The industrialization and modernization of the traditional Chinese functional foods[A];[C];2005
5 WEI Shou-rong, XUE Cun-kuan, HE Xue-bing, SHEN Kai, YUAN Bing, JIANG Peng, ZHU Jun, LI Ying, ZENG Ling Geriatric Institute, Liyuan Hospital, Tongji Medical College, Huazhong Science and Technology University ( Wuhan Hubei, 430077);Effects of Gynostemma polysaccharides(GP)on blood glucose[A];[C];2005
6 Ding Hui (Beijing Food Industry Research Institute,Beijing 100075);The Study by Applying HPLC to Test Simultaneously the Preservatives,Sweeteners and Artifical Colorants in Fruit Flavour Carbonate Beverage[A];[C];1999
7 ;微生物发酵制取功能食品的研究现状[A];[C];2001
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Liu Chao,Chen Guangliang,Zhao Zhiping,et al Director:Wang Qingmao (Anhui College of TCM,Hefei 230038);HYPOGLYCEMIC ACTIVITY OF POLYSACCHARIDES OF MOUTE CORTEX ON NORMAL AND HYPERGLYCEMIC MICE[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;1998-06
2 QUAN Qing zhuan,DANG Rui ye,LI Tong sheng(Shaanxi Institute of Zoology,Xi'an 710032,China);Adsorbing and separating Radish red pigment by X-5 resin[J];Acta Botanica Boreali-occidentalia Sinica;2001-06
3 XU Zi hui, ZHOU Shi wen, HUANG Lin qing (Base of Clinical Pharmacology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China);Extraction and hypoglycemic action of a polysaccharide from the seeds of coix lacchryma jobi var, ma- yuen[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;2000-06
4 ZHANG li-yun PAN Bo-rong (Xinjiang Institute of Ecolegy and Geography, Chinese Academy of Sciences, Urumqi 830011, China );EVALUATION ON EXPLOITATION AND UTILIZATION OF PLANT RESOURCES IN XINJIANG[J];Arid Land Geography;2000-04
5 Huang Lichen,et aL(Institute of drug assay of Qinghai);A STUDY ON ACUTE TOXICITY OF COMPOUND TALNJI CAPSULE[J];JOURNAL OF HIGH ALTITUDE MEDICINE;1996-04
6 Xiao Rong;Wen Liping(School of Pharmacy,West China University of Medical Sciences Chengdu 6l0041);THE SEPAKATION AND ASSAY OF THE ANTIGASTRIC ULCER CONSTITUENTS IN THE OIL OF HIPPOPHAE RHAMNOIDES[J];WEST CHINA JOURNAL OF PHARMACEUTCAL SCIENCES;1996-02
7 Wang Bing,Li Jing,Ma Shubing,et al (Neptunus Bioengineering,CO.,LTD,Shenzhen 518054);THE EXPERIMENTAL STUDY OF SFP ON HYPOGLYCEMIC EFFECT[J];CHINESE JOURNAL OF MARINE DRUGS;2000-03
8 Li Fuchuan, Tang Zhihong, Cui Bowen, Xi Zhenle, Wang Hairen (Deparment of Biology, Shandong University, Jinan 250100);HYPOGLYCEMIC ACTIVITY OF THREE POLYSACCHARIDES FROM LAMINARIA JAPONICA[J];CHINESE JOURNAL OF MARINE DRUGS;2000-05
9 XIE Zun jiang 1* ,LIU Wen qing 2,HE Ye chun 1,LIU Ying 1,ZHANG Zhan bo 1 (1.Department of Anatomy,Harbin Medical University,Harbin\ 150086,China; 2.Department of Anatomy,Qiqihar Medical College,Qiqihar\ 161042,China);INHIBITORY EFFECT OF GINSENG POLYSACCHARIDE AND IL-2 ON MOUSE MELANOMA in vivo[J];Acta Anatomica Sinica;2002-05
10 Li Guiying;Extract the Natural Brown Pigment From Wild Jujube Peel[J];Food Science;1993-08
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