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《Journal of Shantou University(Natural Science Edition)》 1986-01
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Studies on Polysaccharides from Algae——Ⅰ.The Antitumor Activity of Polysaccharides of Sargassum Thunbegii on S180 in Mice and their Effect of Superoxide Dismutase

Zhang Erxian Yu Lijun Zhu Lun Liao Yuwen Huang Wenhua Xiao Zhenfa Yu Jinying (Department of Biology)  
The polysaccharides of ST_1、ST_2 and、ST_3 extracted from sargassum thunbergii inhibit the growth of S_(180).Intraperitoneal injection of ST1-3 solutions at 445mg/kg/d 5% for 10 days will respectively decr- ease the growth of S_(180) by 34.55% (P0.05),55% (P0.05) and 50% (P 0.01).The results of the experiments prove that the ST_2 and ST_3 have a considerable inhibitory effect on tumor. The extract ST_3 has striking effect on the SH group in blood plasma of Mice of Caucer Intraperitoneal injection of the extract ST_3 for 10 successive days can reduce the SH group in blood plasma by 29.59%— 35.45%(P0.01).The extracts ST_1 and ST_3 have a distinct effect on the blood plasma A/G ratio,increasing the globulin concentration of blood plasma by 22—26%.The extract ST_1 has some effect on the superoxide dismutase of the compacted deposits of red cells,decreasing it by 30%.
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