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《Journal of Shantou University(Natural Science Edition)》 1988-01
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Study on Response of Regional Lymph Nodes to Esophageal Carcinoma

Shen Zhongying Wu Mingyao Li Qiaoshan (Shantou Univevsity Medical College)  
Morphological,histochemical and immunohistochemical stud- ies were made of 200 regional lymph nodes from victims of esophageal ca- rcinoma without tumor metastasis.Some of the nodes were examined by virtue of ANAE reaction and IgG fluorescence.It was found that in the early stage,the lymphatic sinuses in lymph nodes usually dilated,with h- yperplasia of the lining endothelial cells and of the intrasinusoidal retic- ular cells.Also,there appeared follicular hyperplasia.In the germinal centres,both pale-stained large lymphocytes and reticular cells containing abundant ANAE positive material were present.The distribution of Ig in reactive lymph follicles varied,a coarse network of Ig being present in the germinal centre and a delicate network of Ig scattering throughout per- ifollicales.Part of the deep cortical units were enlarged and fused into one,with hyperplasia of reticular cells.In the medullary cord,plasma cells were often present in great number,with Ig strongly positive.The group morphological,histochemical and immunohistochemical findings in this of reactive nodes suggested that cellular and humoral immunoreaction occurred in local lymph nodes in response esophageal carcinoma.
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