The Study of Adsorption of Propofol in Plasma with Molecularly Imprinted Polymers
LI Wei-lin, LI Li (Pharmacy College of Xinjiang Medical University, Urumqi, 830054, China)
Objective: Propofol in human plasma was extracted by prepared molecularly imprinted polymers with propofol as tem-plate. Methods: Prepare propofol molecularly imprinted polymers by thermal polymerization, test the performance of polymers, and use them to extract the different concentrations of propofol in plasma. Results: Templates integrated with functional monomers with hydro-gen bonds ; molecularly imprinted polymers adsorbed propofol selectively in human plasma. Conclusion: Molecularly imprinted poly-mers can adsorb propofol in human plasma, and the adsorption rate is influenced by the concentration of substrate.
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Li Zhong1,Wang Xuejun1,Li Xiangyang2 (1.Qinghai Red Cross Hospital;2.Qinghai University Medical College);QUANTITATIVE ANALYSIS OF PROPOFOL IN HUMAN LASMA[J];Journal of Qinghai Medical College;2009-01 |
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JIANG Hong1,REN Yun1,ZHANG Su-pin2,YUAN Heng-jie1,YANG Ya-nan3,WANG Guo-lin2(1.Department of Pharmacy,General Hospital,Tianjin Medical University,Tianjin 300052,China;2.Department of Anesthesiology,General Hospital,Tianjin Medical University;3.Tianjin Stomatological Hospital);Determination of propofol in plasma by HPLC with fluorescence detection[J];Journal of Tianjin Medical University;2007-01 |
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