Bioinformatics Methods for Metabolome Research
LI Lian-wei;ZHANG A-mei;MA Zhan-shan;Faculty of Life Science and Technology,Kunming University of Science and Technology;Computational Biology and Medical Ecology Lab,State Key of Genetic Resource and Evolution,Kunming Institute of Zoology,Chinese Academy of Science;
The metabolome refers to a set of small molecular metabolites. The main purposes of metabolism are the conversion of fuel to energy to run cellular processes. The metabolome can reflect the process of metabolism,As a result,a cell's metabolome can serve as an excellent probe of its function. Cell function abnormality leads to the abnormal changes of metabolom,so metabolome can be assessment standards of the function of cell. The process of extraction and identification of metabolites and the analysis of metabolic data were briefly reviewed,including the pre-processing and network constructed of metabolome datasets.