RETARDATION OF CELL AGING BY LIPID PEROXIDATION. Ⅱ
Zheng Tie-song Zheng Rong-liang (Department of Biology, Lanzhou University, Lanzhou 730000, China)
Fe2+/vitamin C system was used to stimulate lipid peroxidation in human di-ploid fibroblasts derived from embryonic lung tissue to study the relationship between lipid peroxidation and cell senescence. The results showed that certain low levels of lipid peroxidation could evidently improve cellular morphology and prolong 2-8 days of cell survival time. All cellular SOD activities of control and treatment groups decreased with cell subculture. However, SOD activities of treatment groups were not higher than that of the control, which indicated that under certain circumstances SOD would not play an important role in retardation of cell aging.