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《Acta Biologiae Experimentalis Sinica》 2002-01
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IMMUNOCYTOCHEMICAL LOCALIZATION OF ESTROGEN RECEPTOR BETA IN THE RAT BRAIN

ZHANG Ji Qiang CAI Wen Qin SU Bing Yin ZHOU De Shan (Department of Histology and Embryology, the Third Military Medical University, Chongqing 400038, P. R. China)  
The localization of the new estrogen receptor, ER-beta, in the rat brain was studied by immuno-cytochemical technique, and the results revealed that ER-beta immunoactive material was predominantly localized in the neuronal nucleus, but it was also detectable in the cytoplasm and neuronal processes. High levels of ER-beta immunopositive signals were detected in the cerebral cortex, vertical limb of 'the diagonal band, Purk-inje cells, locus ceruleus, and motor trigeminal,nucleus. Moderate levels were found in the medial septum, lateral amygdaloid nucleus, substantia nigra, and central gray. Weak signals were localized in some subregions of the hypothalamus and amygdaloid complex. Some differences of the expression of ER-beta immunoreactivity between male and female rats were also noticed. The above results provide the first detailed evidence that ER-beta protein is widely distributed in the rat brain, and ER-βmay be involved in some important brain function such as learning and memory.
【CateGory Index】: S852.4;
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【References】
Chinese Journal Full-text Database 2 Hits
1 Zhou Hongli;Lin Sen;Yang Ming;Li Shurong;Su Bingyin;Department of Neurobiology,Chongqing Institute of Neurosciences,College of Basic Medical Sciences,Third Military Medical University;Department of Anatomy and Histology & Embryology,Key Laboratory of Development and Regeneration of Sichuan Province,Chengdu Medical College;;Distribution and gender differences of oncomodulin in brain of adult C57 / BL6 mice[J];第三军医大学学报;2014-23
2 CHEN Gui-zhen1,XU Yun-xiang2,WANG Xiao-yun1(1Second School of Clinic Medicine,Guangzhou University of Chinese Medicine,Guangzhou,510120 China;2College of Acupuncture & Massage,Guangzhou University of Chinese Medicine,Guangzhou,510405 China);Thinking on application of metabonomics technologies in mechanism research on treatment of menopausal panic disorder[J];中华中医药杂志;2011-05
【Co-references】
Chinese Journal Full-text Database 3 Hits
1 CHEN Gui-zhen 1,3,XU Yun-xiang 2,ZHANG Jia-wei 2,LIU Song-hao 3,and GUO Zhou-yi 3 1.Second School of Clinic Medicine,Guangzhou University of Traditional Chinese Medicine,Guangzhou (510405),China;2.College of Acupuncture & Massage,Guangzhou University of Traditional Chinese,Guangzhou (510405),China;3.South China Normal University,Guangzhou (510631),China;Effect of Acupoint Catgut-Embedding on the Quality of Life,Reproductive Endocrine and Bone Metabolism of Postmenopausal Women[J];Chinese Journal of Integrative Medicine;2010-06
2 CHEN Gui-zhen1,2,XU Yun-xiang1,ZHANG Jia-wei1,LIU Song-hao2,GUO Zhou-yi2 (1.The Second School of Clinic Medicine,Guangzhou University of TCM,Guangzhou 510405,China; 2.South China Normal University);Effect and safety evaluation of catgut implantation at acupoint for levels of bone metabolism and free radicals in postmenopausal women[J];中国针灸;2010-03
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【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 CHEN Gui-zhen;QIU Xiao-ying;XU Yun-xiang;Bao'an Hospital of Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine;Clinical Medical College of Acupuncture, Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine;;Professor WANG Xiao-yun's experience in the treatment of menopausal emotional disorders[J];中华中医药杂志;2014-11
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