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《Acta Mathematica Sinica(Chinese Series)》 2019-01
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An Additive-Multiplicative Rates Model for Recurrent Event Data with a Terminal Event

Qin SUN;Lian Qiang QU;School of Mathematics and Statistics, Central China Normal University;  
We propose a joint modeling approach for the analysis of recurrent event data with a terminal event, where an additive-multiplicative rates model is specified for the recurrent event process, the Cox hazards frailty model is specified for the terminal event, and the shared frailty is used to account for the association between the two processes. An estimating equation approach is developed for estimating the model parameters. The asymptotic properties of the proposed estimators are established.Simulation studies are constructed to examine performances of the proposed estimators under finite samples. Finally, we use the proposed method to analyze a medical cost study of chronic heart failure patients.
【Fund】: 中央高校基本科研业务费青年教师项目(20205170465)
【CateGory Index】: O212.1
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