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《Shaanxi Journal of Traditional Chinese Medicine》 2015-01
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Shengmai injection preventing constipation after cardiac surgery

Zhu Qi;Chen Zhenqiang;Ye Sheng'ai;Cardiothoracicsurgery,Jiangsu Province Hospital of TCM;  
Objective:Through clinical contrast experiment to observe the clinical curative effect of Shengmai Injection preventing constipation after cardiac surgery.Methods:In the experiment,we selected 42 cases with rheumatic heart value disease who will do open heart surgery under CPB.We randomly divided into experimental group and the control group,21 cases each.Contrasting the differences of defecation situation between two groups.By enzyme-linked immunoassay detection three changes of gastrointestinal hormones.Results:After open heart surgery,the incidence of the experimental group was significantly lower than that in control group(P0.05);Postoperative day 1,day 3,day 6,the VIP,SS concentration of experimental group was significantly lower than that in control group(all P values0.05).The SP concentration of experimental group was significantly higher than that in control group(all P values0.05).Conclusion:Shengmai injection can effectively prevent constipation after cardiac surgery,reduce the incidence of constipation;Shengmai injection can effectively reduce the postoperative levels of VIP,SS,improve the level of SP.
【Fund】: 江苏省中医药管理局课题(LZ11006)
【CateGory Index】: R654.2
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1 WANG Jian,GAO Luan(College of Clinical TCM,Anhui College of Traditional Chinese Medicine,Hefei 230038,China);Commentary on clinical and experimental study based on the theory of "Exterior-interior relationship between the lung and the large intestine"[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-04
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