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《Shaanxi Journal of Traditional Chinese Medicine》 2015-09
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A trial with Xuefu Zhuyu decoction and duloxetine for depression accompanied with pain

Wang Yong;Kang Mingxiu;Mao Zhixia;Department of Integrated TCM and Western Medicine,Tianjin Anding Hospital;  
Objective:To evaluate the effect of Xufu Zhuyu decoction synergizing with duloxetine in alleviating the pain symptom and improving mood in patients with depressive disorder.Methods:63subjects were enrolled in this study from the wards of Dept.Integrative medicine in Anding hospital,from October 2013 to October 2014,who were randomLy divided into 2groups,namely the study group and the controlled group(31for study group and 32 for controlled group);duloxetine alone was applied for patients in controlled group,while Xufuzhuyu decoction,along with duloxetine,was for those in the study group;both groups were assessed with HAMD and VAS at start point,the end of 2weeks and 4weeks of treatment,as well as the endpoint(8weeks).Results:Patients from both groups were much better after 8weeks of treatment;subjects in the study group were with lower HAMD and VAS score than those in the controlled group.Conclusion:Xufu Zhuyu decoction synergizing with duloxetine can improve the mood and alleviate pain in patients with depressive disorder.
【CateGory Index】: R749.4
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