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《Experimental Technology and Management》 2017-01
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Comparison of success rate made by students' two kinds of acute renal insufficiency models in rabbits independently

Tian Wei;Gong Yanping;Ma Shangyin;Basic Medical College,Inner Mongolia Medical University;Inner Mongolia People's Hospital;  
Objective To compare the successful rate of two methods of acute renal insufficiency in rabbits by students,so as to explore which method will appropriate student's experiments.Methods Forty groups of students were randomly assigned to two groups to establish model of rabbits with acute renal insufficiency using methods of HgCl_2 poisoning and ischemia-reperfusion,according to the blood urea nitrogen and serum creatinine to evaluate the success rate of students using two modeling methods.Results The successful rate of students coped the of ischemia reperfusion renal insufficiency model was higher than that of HgCl_2 toxic model(P0.05).Conclusion Ischemia reperfusion injury model of acute renal insufficiency method is safe,nontoxic,no discharge of the three wastes,which can be completed within a limited time teaching experiment,and the operational difficulty is appropriate,the operation is easy around the experimental control,and the experiment works well.It can be used for other medical functional scientific teaching experiments.
【Fund】: 内蒙古医科大学实验室开放基金指南型项目基金(kfsyszn201416)
【CateGory Index】: R-4;G642.4
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