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The Changes of T Cell Subpopulation of Peripheral Blood in Child Patients with Recurrent Respiratory Infection

Qiu Cheng, et al Air Force Hospital of Nanjing  
Objective To search for the relationship between recurrent respiratory Infection(RRI)and the changesof T cell subpopulation of peripheral blood in child patients. Design Case-control research Patients and Other Participants Thirty-two cases of RRI, 21 male and 11 female. There are 20 health children in control group, 13 male and 7 female. Interventions The blood of all the patients and participants were drawn and delivered for measurementat 8 o' clock in the morning. Measurements and Main Results The peripheral blood T cell subpopulation of 32 cases and 20 healthchildren had been determined by OKT monoclonal antibody. The results show that OKT_3 percentages ofRRI group and control group are 56.21±7.19 and 61.42±4.87 (P0.01), OKT_4 are 37.27±3.45 and39.35±3.52 (P0.05). OKT_8 are 30.69±3.94 aud 28.14±4.22 (P0.05) respectively. The values ofOKT_4 /OKT_8 of the two group are 1.31±0.14 and 1.41±0.16 (P0.05) respectively. Conclusions The peripheral blood OKT_3 and OKT_4 are decreased, OKT_8 are incrcased in the childpatients with RRI, OKT_4 /OKT_8 is decreased. It is suggested that the cellular immune function wouldbe decreased and the proportion of T cell Subpopulation would be imbalance in child patients with RRI.
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