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《JOURNAL OF APPLIED CLINICAL PEDIATRICS》 1997-01
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Interrelation of iron parameters change in course of ferralium treatment in iron-deficiency anemia

Wu Manyi; Chen Juening; Yang Huimin;Liao Guoyi;Yu Ling; Yu Ming; Wang Ruwen(Depertment of Pediatrics,Affiliated Hospital of Medical College,Jinan University,Guangzhou,P. R. China Department of Nuttition,China development Center of Children)  
objective To searcb for the interrelation of iron parameters changr in course of ferralium treatment in iron- deficiency anemia.Methods There were 29 caare of iron-deficiency anemia treated with ferplex,ferralium(4mg·kg-1·d-1 )for 40 days.The changes of every parameter of iron such as serum ferritin (SF), zinc protoporphyrin (Zpp), hemoglobin (Hb), reticulocyte (Ret)were observed before treatment and after lst, 3rd. 5th, 6th week of treatmet. The interrelational figure was made by regarding normal value as the coordinate, and the value of every parameter of iron as the ordinate.Results The line of detived value of SF cooss with that of normal value after 5~6 days of treatment. The Zpp line is decreaed slowly along with the treatment,and cross with normal value line after 5~6 weeks of treatment. The Hb line is increaed rapidly after 3 weeks of that,and croas with normal value line about after 4 weeks of that. The Ret is incrend obviously and reach peak at the lst of treatment,and fall to normal value at 3rd week of treatment.Conclusion Observing the interrelation of every iron parameter in course of treating iron-deficiency anemia with ferralium has important aiguificance to understand the condition of iron equilibrium and aasess the clinical therapeutic effects.
【CateGory Index】: R556
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