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HCV infection in patients with infantile hepatitis syndrome

YAN Pu;SU Yan-Li;CHEN Guang-Hua; ZHANG Mei-De; CHEN Zheng-Rong;ZENG Rong-Xin;ZHENG Xiu-Xia; TANG Zhen- Ya; HAO Lian-Jie(Guangzhou children's Hospital,Tongji Hospital, Tongji Medical University)  
Objectives To investigate for HCV infection and its route of transmission in patients with infantile hepatitis syndrome in Guangdong area.Methods Anti-HCV and HCV RNA in serum were detected by ELISA and PCR respectively.Results Eleven out of 90 infants with hepatitis were positive for HCV marks. The positive rate Was 12. 2 % (11/90). Among of them 4 cases had simultaneously anti-HCV and HCV RNA. The other positive patients included 3 cases with antiHCV and 4 cases with HCV RAN.Conclusions The results indicated that HCV infection is an important factor in infantile hepatitis syndrome in Guangdong area. The route of transmission in the HCV positive patients was mainly related to using blood and its products. The second was mother to infant transmission.
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