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The diagnostic value of serum neuron specific enolase and SPECT rCBF imaging in children status epiliptics

OU YANG Ying,PENG Qian,MU Faguang,et al. Sichuan Provensial Hospital, Chengdu 610072, P.R. China  
Objective To evaluate the diagnostic value of serum neuron specific enolase and SPECT rCBF imaging in children status epiliptics(SE).Methods Serum NSE was performed in 28 of SE and 40 normal controls. SPECT rCBF imaging was performed in 15 of SE.Results The mean serum NSE in SE patients was 15.13± 6.22 μg/L, which was higher than that of normal controls(mean 2.635± 0.765 μg/L, P0.001); The SPECT rCBF imaging abnormal rate in 15 of SE was 73.4 %.Conclusions Children SE can cause brain injury. The serum NSE is a reliable marker of brain injury in children SE. SPECT rCBF imaging abnormal in children SE can help diagnosing brain injury.
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