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Delivery mother and umbilical blood lead level and infant neuro-behavioral development

LIU Xirong, QIN Rui, ZHAO Renzheng, et al. The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, P.R. China  
Objective To explore the significance of the delivery mother and umbilical blood lead level as a indicator of fetus lead exposure in evaluating the effects of low level lead exposure during pregnancy on neuro behavioral development of infants.Methods The delivery mother blood and umbilical blood lead level were matched ,and T test was done to analyze Bayley scale record in infants of 3 , 6 months.Results There was a significant correlation between the mother blood lead and umbilical blood lead; while there was a remarkably negative correlation between the mother blood lead and MDI and PDI of 3 months and MDI of 6 months. With mother blood lead of 50th percentile as a cutoff values, there is a significant difference in MDI and PDI of 3, 6 months infants.Conclusions Low level lead exposure during pregnancy can have harmful effects on infants neuro behavioral development. Mother blood lead as a indicator of lead exposure during pregnancy is more desirable than umbilical blood lead.
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