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《Journal of Applied Clinical Pediatrics》 2009-01
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Etiopathogenisis of Femoral Artery Thrombosis during Interventional Therapy for Congenital Heart Disease

WANG Jun,XIE Qi-lian,GAO Lei,LV Ying,SUN Li-ying,ZHOU Jin,ZHANG Mi-lin(Center of Congenital Heart Disease,the First Hospital of Hebei Medical University,Shijiazhuang 050031,Hebei Province,China)  
Objective To explore the cause and prevention measure of femoral artery thrombosis during interventional therapy for congenital heart disease(CHD)in children.Methods From May.2004 to Aug.2006,in the First Hospital of Hebei Medical University,interventional procedures were performed in 962 children with CHD.All of the 962 subjects accorded with interventional indication and 6 of them(4 male and 2 female)who suffered from femoral artery thrombosis after transcatheter closure were given thrombolysis therapy.The data of the 6 cases were analyzed.Results Femoral artery thrombosis were found in 6 cases(0.63%)and all of them were dealt with intravenous thrombolysis early.The early intravenous thrombolysis therapy was succeeded in 3 cases.For the 3 cases unsucceeded,local transcatheter closure thrombolysis was performed in 2 cases and succeeded,intravenous thrombolysis and anticoagulant therapy were lasted in the other case and collateral circulation compensation was found by ultrasonography 1 week later.The diameter was respectively 40%,70%,80%of contralateral femoral deep artery after postoperation 1 month,6 months and 12 months.Left dorsalis pedis arteries skin temperature and pulsation was normal after postoperation 1 month.The other 5 cases recovered well.No limb necrosis happened.Conclusions Early intravenous thrombolysis and local transcatheter closure thrombolysis therapy on femoral artery thrombosis during interventional therapy for CHD in children is efficient.Positive perioperative management and strict dangerous factors control may be reduce the incidence of femoral artery thrombosis.J Appl Clin Pediatr,2009,24(1):33-34
【CateGory Index】: R725.4
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