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《Journal of Applied Clinical Pediatrics》 2009-01
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Clinical Manifestation and Video-Electroencephalogram Featurs of 60 Infantile Spasm

JIN Rui-feng1,WANG Ji-wen2,GAO Zai-fen1,TIAN Guang-yan1,YU Zhen-hua2,SUN Ruo-peng2(1.Department of Neurology,Qilu Children's Hospital of Shandong University;2.Department of Pediatrics,Qilu Hospital of Shangdong University,Jinan 250022,Shangdong Province,China)  
Objective To investigate ictal and interictal electroencephalogram(EEG)characters of infantile spasm and to evaluate treatment responses by video-EEG(VEEG)on the oneset and during the onset.Methods Clinical data and VEEG findings were subject to the comparison in 60 cases(43 male and 17 female,aging 1-12 months)based on long term recordings by type 1161B VEEG.VEEG analysis was performed visually for interictal background activity,ictal events:spasms and other seizures either generalized or partial,high voltage slow wave complex,fast wave bursts,and desynchronization.Results Three hundred and eighteen seizures(including 105 clusters of spasms,98 isol spasms and 115 other spasms)were recorded by EEG and 263 seizures were recorded by VEEG in 60 patients.The infantile spasm was endeictic if with partial seizures.Seizures at awake time were 36 cases and at sleep period were 24 cases。Among the 60 patients,flexor type 42 cases,extensor type 7,cases and mixed flexor/extensor type 11 cases.Thirty-five cases were symmetrical spasms,most of which were cryptogenic,symptomatic spasms cauld be seen too.And asymmetrical spasms were 25 cases(21%).Drug therapy could not relieve partial seizure onset.Conclusions Specifical changes in VEEG,which are very important to the diagnosis of West syndrome,may contribute to etiologic diagnosis and prognostic evaluation.J Appl Clin Pediatr,2009,24(1):56-57
【CateGory Index】: R742.1
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