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《Journal of Applied Clinical Pediatrics》 2009-01
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Research Progress of Pathogenesis of Atherosclerosis

LI Wei,DU Jun-bao(Department of Pediatrics,Peking University First Hospital,Beijing 100034,China)  
Atherosclerosis(AS)is a chronic inflammatory disease of arteries,induced by the injury of endothelial cells,accumulation of mononuclear macrophage and lipid,proliferation of smooth muscle cells and the adhesion of platelets.As a frequent disease and a common pathology in cardiovascular system.In fact,the inciting event of AS is likely an inflammatory insult that occurs decades before the disease becomes clinically apparent.More and more cases were also reported in the childhood recently.Therefore it is important both for clinic and research to investigate the cause and pathogenesis of AS.J Appl Clin Pediatr,2009,24(1):58-60
【Fund】: 国家自然科学基金项目资助(30425010;30630031;30571971);; 北京市自然科学基金项目资助(7052043 7072082);; 国家重点基础研究发展规划项目资助(2006CB503807);; 国家长江学者奖励计划项目资助
【CateGory Index】: R543
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