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《Journal of Applied Clinical Pediatrics》 2009-02
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Analysis of Risk Factors for Survival of 309 Very Low Birth Weight Infants

LUO Li-qian1,ZHOU Ping2,XIAO Xin3,LI Si-tao3(1.Department of Neonatology,the First Affiliated Hospital of Jinan University,Guangzhou 510630,Guangdong Province,China;2.Department of Neonatology,Maternal and Child Health Hospital of Bao'an District of Shenzhen,Shenzhen 518100,Guangdong Province,China;3.Center for Perinatology,the Sixth Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510655,Guangdong Province,China)  
Objective To investigate the high risk factors for the survival of very low birth weight infants(VLBWI)and the relative factors for influencing survivability on VLBWI.Methods Three hundred and nine VLBWI hospitalized in our hospital from Jan.2002 to Dec.2007 were divided into 3 groups according to the weight,as:less than 1 000 group,1 001-1 250 group,1 251-1 500 group.Then the general clinical data,clinical prognosis,common complication of the cases were reviewed.Results There were 180 cases who had cured,the cure rate was 58.3%.The cure rate increased as the infant weight went up(P=0.01).There were 16 infants dead,mortality was 5.17%,which was lower as the weight increased(P=0).The risk factors causing the premature birth of VLBWI were related to the multiple births(33 cases,10.68%),early amnion breaking(87 cases,28.15%),pregnancy complications(including pregnancy induced hypertension syndrome(PIH),placental abruption and placenta previa)(66 cases,21.36%),practice-premature(13 case,4.21%),chronic illness in gestation(24 cases,7.77%)and unclear reasons(86 cases,27.83%).All hospitalized VLBWI had at least one complication including respiratory distress syndrome(105 cases,33.98%),pneumonia(71 cases,22.97%),intraventricular hemorrhage(56 cases,18.12%),apnea(50 cases,16.18%),patent ductus arteriosus(9 cases,2.90%),septemia(6 cases,1.94%).The predominant causes of death were bleeding in the lungs,breath-embarrassment-synthesis,infection and encephalic bleeding.Conclusions It is important to strengthen the recognition of the high risk perinatal factors of the VLBWI,to prevent premature,to prolong its gestational age as far as possible,and to take combined therapy to avoid the complication in order to reduce mortality and improve its quality of life.
【CateGory Index】: R722
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