Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Applied Clinical Pediatrics》 2009-22
Add to Favorite Get Latest Update

Clinical Features of Epidemic Cerebrospinal Meningitis of Children in Shanghai Area during 2006 to 2008

LU Yi,WANG Xiao-hong (Department of Infectious,Children′s Hospital of Fudan University,Shanghai 201102,China)  
Objective To investigate the epidemiology and clinical features of epidemic cerebrospinal meningitis of children in Shanghai area in the last 2.5 years. Methods A retrospective study was conducted in 27 hospitalized patients with epidemic cerebrospinal meningitis by analyzing the clinical manifestation,epidemiology and laboratory test fingdings from Jan.2006 to Jun.2008.Statistical analysis of the clinical manifestations of cases in serogroup A,B and C was performed according to Neisseria meningitidis infection. Results There were sporadic cases of children with epidemic cerebrospinal meningitis in Shanghai area in the last 2.5 years.The seasonal distribution illustrated the peak occurrence from Feb.to Apr.Among all these cases,92.6% were floating children.Common types(74.1%) were the predominant clinical manifestations and the others were fulminate types(25.9%).Four cases in each of serogroup A and B,and 8 cases of serogroup C were identified by serotyping on 14 Neisseria meningitidis strains and genotyping on the other 2 cases′ cerebrospinal fluid specimens.All the patients in serogroup A with meningococcal diseases were not vaccinated before and 25.0% of them belonged to fulminate types.Half of the cases had petechia on the skin and the prevalence of skin necrosis was 25.0% and 50% had complications of nervous system.No fulminate type was present in cases of serogroup B meningococcal disease and only 1 case had slight petechia on the skin.However,intensive convulsions occurred in 75.0% of the patients,and all of them had complication of nervous system,with a few had sequela.Among the patients in serogroup C meningococcal disease,62.5% patients were vaccinated with serogroup A Neisseria meningitidis.In serogroup C,Neisseria meningitidis infection was found in each age group,with petechia on skin,skin necrosis,immunity correlation fever and complications of nervous system in 87.5%,50.0%,75.0% and 12.5% of the patients,respectively. Conclusions 1.Epidemic cerebrospinal meningitis occurred sporadically in children in Shanghai area,the majority of patients were floating populations.2.Clinical manifestation was typical in patients of serogroup A meningococcal disease.Subdural effusion or ventricalitis was more common in patients of serogroup B meningococcal disease.In serogroup C,Neisseria meningitidis was the most prevalent serotype leading to epidemic cerebrospinal meningitis.More cases were found in patients infected with serogroup C,Neisseria meningitidis with severe shock and immunity correlation fever compared with the other groups.Prophylactic vaccination of serogroup C polyvalent meningococcal organism should be recommended.
【CateGory Index】: R725.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 6 Hits
1 XU Xi-hai,YE Jun,LI Jia-bin,JIN Yu-hui(The First Affiliated Hospital of Anhui Medical University,Hefei Anhui 230022,China);Clinical analysis of 53 cases with epidemic cerebrospinal meningitis group C[J];Anhui Medical and Pharmaceutical Journal;2007-07
2 LI Yuefang, ZENG Mei, WANG Xiaohong, WANG Daiming. (Department of I nfectious Diseases, Shanghai Children's Hospital, Fudan University, Shanghai 200 032, China);Clinical epidemiology of epidemic cerebrospinal meningitis in children in Shanghai area from 1984 to 2003[J];Chinese Journal of Infection and Chemotherapy;2004-06
3 WANG Xiao-ping,JIN Yu-hui,WANG Hai.(Hefei City Center for Disease Control and Prevention,Hefei 230061,China);ANALYSIS ON EPIDEMIC CHARACTERISTICS OF EPIDEMIC CEREBROSPINAL MENINGITIS FROM 2004-2006 IN HEFEI[J];Modern Preventive Medicine;2008-11
4 LI Yi-xing,LI Jun-hong,YIN Zundong,et al.(National Immunization Programme,Chinese Center for Disease Control and Prevention,Beijing 100050,China);Epidemiological Characteristic Analysis of the Meningococcal Disease in China During 2005-2006[J];Chinese Journal of Vaccines and Immunization;2007-03
5 LI Jun-hong,NING Xia,LI Yi-xing,et al.(National Immunization Program,Chinese Center for Disease Control and Prevention,Beijing 100050,China);Analysis of Results of Meningococcal Disease Key Surveillance Provinces in 2006[J];Chinese Journal of Vaccines and Immunization;2007-06
6 LI Yi-xing,LUO Hui-ming,LI Jun-hong,et al.(National Immunization Program,Chinse Center for Disease Control and Prevention,Beijing 100050,China);Analysis on Epidemiological Characteristic of the Meningococcal Meningitis in China During 2006-2007[J];Chinese Journal of Vaccines and Immunization;2008-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 KE Wen-hong,LI Yu,ZHANG Wen-yan,LI Dong-liang,CHEN Xia,YAN Kai-li(Hefei Center for Disease Control and Prevention,Hefei,Anhui 230061,China);Analysis of Laboratory Result on 155 Epidemic Cerebrospinal Meningitis Suspect Cases[J];Anhui Journal of Preventive Medicine;2009-01
2 XU Xi-hai,YE Jun,LI Jia-bin,JIN Yu-hui(The First Affiliated Hospital of Anhui Medical University,Hefei Anhui 230022,China);Clinical analysis of 53 cases with epidemic cerebrospinal meningitis group C[J];Anhui Medical and Pharmaceutical Journal;2007-07
3 DENG Xiu-ying BI Cheng(Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009 China);Results of detecting of drug resistance of Neisseria meningitides to 12 antimacrobial agents in Jiangsu province[J];Jiangsu Health Care;2008-04
4 Huang Rong-na,Zhang Xiao-chun,Yang Xiao-xing,et al.(Chengdu Center for Disease Control and Prevention,Chengdu 610041,China);Analysis on Neisseria Meningitidis Carraige Status of Residents in Health Population in Chengdu District[J];Strait Journal of Preventive Medicine;2009-04
5 LI Xiao(Linyi Municipal Center for Disease Control and Prevention,Linyi 276001,Shandong,P.R.China);Analysis of prevalent trend of epidemic cerebrospinal meningitis in 1988~2007 in Linyi City[J];China Tropical Medicine;2009-06
6 YIN Chi-biao, ZHANG Fu-chun, WANG Jian, JIA Wei-dong, LI Ling-jun, CHEN Yan-qing, GONG Lan ,TANG Xiao-ping(Guangzhou No.8 People's Hospital,Guangzhou 510060,China);Clinical Manifestation and Laboratory Examination Results Analysis of 29 Cases of Epidemic Cerebrospinal Meningitis of Guangzhou in 2005[J];Journal of Tropical Medicine;2005-05
7 ZHANG Yong,LAI Zhi-fa,ZHOU Hai-tao,et al(Futian District Center for Disease Control and Prevention,Shenzhen 518040,Guangdong, P. R.China);Pathogenic analysis of epidemic cerebrospinal encephalitis cases[J];China Tropical Medicine;2009-08
8 YAN Shao-hong1,ZHANG Hong-fei2,LIU Tian-ying3(1 Inner Mongolia Provincial Center for Disease Control and Prevention,Huhhot 010031,China;2 Tong liao city Center for Disease Control and Prevention,tong liao 028000,China;3 Zha lu te county Center for Disease Control and Prevention,lu bei 029100,China;);Observation on the safety and immunogenicity of group A+C meningococcal polysaccharide vaccine[J];Progress in Microbiology and Immunology;2009-02
9 ZHANG Li,LUAN Rong-sheng,CHEN Gan-ne,et al.(Guizhou Center for Disease Control and Prevention,Guiyang 550004,China);EPIDEMIOLOGICAL ANALYSIS ON EPIDEMIC CEREBROSPINAL MENINGITIS IN GUIZHOU FROM 2001 TO 2006[J];Modern Preventive Medicine;2008-06
10 JIANG Hai-quan(Department of Infectious Diseases,People′s Hospital of Quxian County,Quxian 635200,China);Clinical and epidemiological analysis of 97 cases of epidemic cerebrospinal meningitis[J];Guide of China Medicine;2008-18
【Secondary Citations】
Chinese Journal Full-text Database 8 Hits
1 LI Yuefang, ZENG Mei, WANG Xiaohong, WANG Daiming. (Department of I nfectious Diseases, Shanghai Children's Hospital, Fudan University, Shanghai 200 032, China);Clinical epidemiology of epidemic cerebrospinal meningitis in children in Shanghai area from 1984 to 2003[J];Chinese Journal of Infection and Chemotherapy;2004-06
2 TAN Yongkang.Beijing Youan Hospital, Beijing 100054,China;Progress in epidemic cerebrospinal meningitis[J];Journal of Clinical Internal Medicine;2001-04
3 ZHU Zhan - ying, LI Dong - yue, HUANG Guo - chao, et al. ( Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 510300, Gaungdong, P. R. China);The prevalence of epidemic encephalitis and immune prevention.[J];China Tropical Medicine;2005-04
4 Hu Xu jing Institute of Epidemiology and Microbiology,Chinese Academy of Preventive Medicine,Beijing 102206,China;Epidemiological Surveillance and Prophylaxis of Epidemic Cerebrospinal Meningitis[J];Chinese Journal of Vaccines and Immunization;2001-05
5 LIU Dan-qing,WANG Bin-bing,CHEN Xia,et al.(Anhui Provincial Center for Disease Control and Prevention Hefei,230061,Anhui,China);Epidemiological Analysis and Control Methods for Epidemic Cerebrospinal Meningitis in Anhui Province During 2004-2005[J];Chinese Journal of Vaccines and Immunization;2006-01
6 WANG Xiao-ping,JIN Yu-hui,HUANG Hong-yan (Hefei Center for Disease Contiol and Prevention,Hefei 230061,Anhui,China);Analysis on Cerebrospinal Meningitis in Hefei City in 2004[J];Chinese Journal of Vaccines and Immunization;2006-01
7 XU Li,SHAO Zhu-jun,GAO Yuan,et al.(Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China);Surveillance on Pathogens of Meningococcal Meningitis in China,2004-2006[J];Chinese Journal of Vaccines and Immunization;2007-03
8 ZHANG Tie-gang,HE Xiong,CHEN Li-juan,HE Jing-guo, YANG Jie,SUN Mei-ping,SHAO Zhu-jun ,CHEN Zhi-hai, ZHAO Hui.Institute of Immunization and Prevention of Beijing Center for Disease Prevention and Control, Beijing 100013, China;Surveillance on pathogens of meningococcal meningitis in Beijing,2005[J];Chinese Journal of Epidemiology;2006-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved