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Differences of Age and Gender in Children with Orthostatic Hypotension

YUAN He-li1,HE Zhi-xiang2,WANG Cheng1,WU Li-jia1,LIN Ping1,ZHU Li-ping1,KANG Mei-hua1(1.Cardiovascular Laboratory,Department of Pediatrics,the Second Xiangya Hospital,Central South University,Institute of Pediatrics of Central South University,Changsha 410011,Hunan Province,China;2.Department of Internal Medicine,Hunan Children′s Hospital,Changsha 410007,Hunan Province,China)  
Objective To explore the differences of age and gender in children with orthostatic hypotension(OH).Methods A total of 1 158 cases of pediatric patients with unexplained syncope,headache,dizziness in syncope specialist children′s clinic of the Second Xiangya Hospital,Central South University,were chosen from Jan.2000 to May 2010.Forty-five patients with OH were diagnosed among 1 158(597 cases were male and 561 cases were female) ones with syncope and dizziness by head-up tilt table test(HUTT),who were 3.1-17.0 years old,mean(10.72±2.80) years old.The patients were divided into ≥12 years old group and 12 years old group according to the age.The course of disease,diagnostic rate,changes of blood pressure in OH children and their relationship with age and gender were analyzed.Results 1.The diagnostic rate:the diagnostic rate of OH was not different in age and gender(χ2=0.631,0.584;Pa0.05).2.The course and onset age of OH:the course was 0.03-60.00(8.13±14.06) months in 12 years old group,which was not different in gender [(4.77±7.86) months vs(10.59±17.10) months;t=0.634,P0.05)].In ≥12 years old group,the course was 0.30-72.00(20.10±22.20) months,there was no difference in gender [(16.55±1.80) months vs(26.03±2.87) months;t=0.273,P0.05].There was no diffe-rence of course between the different age groups[(8.73±16.07) month vs(20.11±22.20) month;t=1.932,P0.05].3.Changes in blood pressure of OH children:there was no difference in systolic and diastolic blood pressure decline within 3 minutes during HUTT between ≥12 years old group and 12 years old group(t=1.495,0.079;Pa0.05).In 12 years old group,there was no difference in systolic and diastolic blood pressure decrease within 3 minutes during HUTT in gender(t=0.019,1.730;Pa0.05).In ≥12 years old group,there was no difference in systolic and diastolic blood pressure decrease within 3 minutes during HUTT in gender(t=0.364,0.843;Pa0.05).Conclusions There is no difference in the course of disease and systolic and diastolic blood pressure decrease within 3 minutes during HUTT of OH in age and gender.There is also no difference of age and gender either in the diagnostic rate.
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