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《Journal of Applied Clinical Pediatrics》 2012-24
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Efficacy of Erythromycin Cydocarbonate in Treatment of Acute Respiratory Tract Infections in Children

ZHENG Bao-ying,CAO Ling(Department of Respiratory Medicine,Capital Institute of Pediatrics,Beijing 100020,China)  
Objective To evaluate the efficacy and adverse reactions of erythromycin cydocarbonate suspension in treatment of acute respiratory tract infections in children.Methods Sixty-three patients with acute respiratory tract infections were randomly divided into group A(29 cases) and group B(34 cases).Group A were treated with erythromycin cydocarbonate,15 mg·kg-1,twice per day;the patients in group B were treated with azithromycin,10 mg·kg-1,once per day.And the fever time and clinical signs were observed to compare the cure rate,effective rate and side-effect incidence,all the records were analyzed.Results The cure rates were 51.72% and 61.76% respectively in the group A and group B,there was no significant difference(P0.05).The effective rates were 89.66% and 88.24% respectively in the group A and group B with,there was no significant difference(P0.05).Comparing the symptoms and signs such as fever,cough,etc,there was no significant difference between the 2 groups.Only 1 patient in group A complained of nausea,vomitting,loss of appetite,which could be tolerated and had no influence on therapy.Conclusions Erythromycin cydocarbonate suspension is effective and safe in treatment of acute respiratory tract infections in children,which has no significant difference with azithromycin suspension.
【CateGory Index】: R725.6
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