Serum microelement spectrum, measurement and significance of T cell subgroup of peripheral blood in child Patients with recurrent respiratory tract infection
FENG Xue-Bin; LIU Feng; FANG Chong-Yun;HUANG Wei; MA Yong-Hong; YU Shu-Li(Department of Pediatrics, Fathophysiology Biology, Binzheng Medical College)
Objectives To search for the levels of the serum microelements, the measurement and significance of T cell subgroup of peripheral blood in child patients with recurrent respiratory tract infection (RRTI).Methods There were 92 children (58 males and 34 females)with RRTI in RRTI group,ahd 42 healthy children in control group. The 3 ￣ 5ml venous blood of them was drawn at 7 ￣ 9 0' clock in the morning (anticoagulated by heparin). The serum microelement spectrum was determined by spectraspan -V type of DCP-AES and 12 kinds of micro elements (Zn, Mn, Al, Cd, Fe, Pb, Cu, Ni, Ti, Co, Li and Cr) were determined at the same time. T cell subgroup and T cell proliferation function were determined respectively by erythrccyte-antibody rosette and 3H-TdR incorporation methods.Results The levels of serum microelements, Zn, Ph, Ni, Co, Li, Fe and Ti in RRTI group are lower than that in control group. The percentage of T-cell subgroup in peripheral blood, CD3+, CD4+, thevalue of CD4+/CD8+,T cell proliferation function and the levels of serum IgG in RRTI group are lower than that in control group.Conclusions There are extensive injuries of immunologic function in child patients with RRTI. Lacks of microelements should play an important role in occurrence and development of RRTI.