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《Journal of Shaoyang University(Natural Science Edition)》 2018-05
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HBP Expression Level and Sepsis Prediction

KONG Lirui;HUANG Shenhua;HUANG Hengjian;Traditional Chinese Medicine Hospital of PI County,Chengdu;West China Hospital of Sichuan University;  
Heparin-binding protein(HBP) is a multifunctional protein with broad antibacterial and chemotactic activity,which plays crucial role in the occurrence and development of sepsis. HBP is released immediately upon infection and then functions on the target cell,which acts as an amplifier of inflammatory responses.As a kind of granular release protein,HBP has been shown to correlate with bacterial infection.Recently,HBP was described as a useful biomarker with extensive window period and the characteristics of being early,specific and sensitive,which was superior to traditional inflammatory markers.Consequently,HBP has the potential clinical application value for sepsis prediction and treatment.
【CateGory Index】: R459.7
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