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《Practical Preventive Medicine》 2007-02
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Effect of Maxin Shigan Decoction and its Alteration on Mice T-cell Subpopulation Exposured to Influenza Virus A

ZHAO Wu-neng,LU Fang-guo,ZHANG Wei,et al.(1.Traditional Chinese Medicine University of Hunan,Changsha 410007,Hunan,China; 2.Hunan Agricultural University,Changsha 410200,Hunan,China)  
Objective To investigate the effect of maxin shigan decoction(MSD) and its alteration on mice T-cell subpopulation exposed to influenza virus A.Methods The models were established by inoculating with the influenza virus A fitted to lung via mice nose in mice and then divided into 10 times of MSD,5 times of MSD,infected model and normal control groups.The normal salt solution was filled up in the control and infected groups and the drug MSD in relevant concentration in the other 2 groups,1 time per day,each time with 0.4ml,and lasted for 8 days. The water or drug was forbidden for 8 hours after the last time of filling up,and then,the percentage of T-cell subpopulation was measured from the experimental animals.Results The percentages of CD3+ and CD4+T-cell subpopulation and the ratio of CD4+/CD8+ in the 10 times MSD group were significantly higher than those in the infected model group(P0.05) while the percentage of CD8+T-cell subpopulation was significantly lower than that of the infected model group(P0.05).The percentages of CD8+T-cell subpopulation in both 10 and 5 times of MSD groups were significantly lower than those of the infected model group(P0.05).Conclusion MSD in the largest dosage(10 times of clinical dose) and supplemented MSD in the largest dosage(5 times of clinical dose) can obviously regulate the percentage of T-cell subpopulation in mice exposed to influenza virus A.
【Fund】: 湖南省自然科学基金资助项目(06JJ20055)
【CateGory Index】: R285.5
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1 XIONG Da-sheng XI Zai-xin DENG Ying-wei (Biology Department of Changed Teachers University, Changde Hunan,415000);STUDIES OF THE ANTIMICROBIAL EFFECT OF THE EXTRACTS OF Houttuynia cordata[J];Journal of Changde Teachers University;2002-04
2 WANG Li-Jie, LIU Chun-Feng, YUAN Zhuang, et al. (Department of Pediatrics, Second Clinical College, China Medical University, Shenyang 110003, China);Determination of Tumor Necrosis Factor-α in Children with Pneumonia and the Systemic Inflammatory Response Syndrome[J];Chinese Journal of Contemporary Pediatrics;2002-02
3 Yu Hong, et al Prouincial Institute of Food Hygiene of Guizhou;The Effect of Taraxacum Mongolicum on Immune Function in Mouse[J];JOURNAL OF GUIYANG MEDICAL COLLEGE;1997-02
4 Luo Zhonghua , Huang Wenhua , Liu Jing , et al. Burnresearch Institute,The Third Military Medical University. Chongqing 630038;^EFFECTS OF CHINESE HERBS ON NEUTROPHILS AFTER THERMAL INJURY IN MICE[J];MEDICAL JOURNAL OF CHINESE PEOPLE'S LIBERATION ARMY;1994-04
5 Wen Guohui,Wu Yong.GuangDong Medical College,ZhanJiang 524023.;To compare TNF-α、IL-6 and CRP when in acute infection[J];Chinese Journal of Laboratory Medicine Education;2005-02
6 FENG Jian-fei, WANG Jun, ZHANG Li, et al.Department of Pediatrics, the third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China;The value of interleukin-8 and C-reactive protein as a test for neonatal infections[J];Pediatric Emergency Medicine;2004-04
7 SHI Shide;ZHOU Minwei;LI Jianjun;ZHENG Wenling Dept. of Medical Laboratory, General Military Hospital of Guangzhou, Guangzhou 510010, China;Effect of Jiedu Lifei Oral Liquid on Immune Function in Mice with Viral Pneumonia[J];Journal of Guangzhou University of Traditional Chinese Medicine;2004-01
8 LI Tongming,WANG Guixiang,QUAN Shijian,GAO Jie,WANG Peijian(College of Chinese Materia Medica,Guangzhou University of TCM,Guangzhou 510405,China);Effect of Ma Xing Shi Gan Decoction on Metabolism of Oxygen Free Radicals in Mice with Bronchial Asthma[J];Journal of Guangzhou University of Traditional Chinese Medicine;2006-06
9 Dong Jiede Chen Chenhua Qiu Suying Yu Xiuping Zhao Weiming Dept.of Microbiology,Shandong Medical University,Jinan,250012;STUDIES ON THE EFFECTS OF FOUR HERBAL MEDICINES TO COX B_3 AND ECHO 19 VIRUSES[J];;1993-04
10 JIN Ku-gen,WU Cheng-xun(The People's Hospital of Gaoping City,Shanxi,048000,China);Acute Attack of Pulmonary Heart Disease Treated with Integrated WM and TCM,a Report of 43 Cases[J];Shanxi Journal of Traditional Chinese Medicine;2003-02
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