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《Practical Preventive Medicine》 2007-02
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Side Effects on Blood System in IFNa-2b Against Hepatitis C

JIANG Jian1,2,LI Deng-qing1,LI Juan2,et al.(1.Department of Medical Laboratory,Xiangya Medical College of Central South University,Changsha 410013,Hunan;2.Futian District Hospital of Traditional Chinese Medicine,Shenzhen 518034,Guangdong)  
Objective To investigate the blood changes in chronic hepatitis C patients cured with IFNa-2b.MethodsAccording to the dosage of IFNa2b,42 patients were assigned into two groups,one group was treated with 3MU,and another group with 5MU.SYSMEX KX-21 was used to detect the patient's white blood cell,hemoglobin and platelet before and after taking the IFNa-2b therapy. ResultBefore treating with IFNa-2b,the levels of WBC,HGB and PLT in these two groups showed no statistical difference,while after the treatment,white blood cell and platelet stepped down differently in a dose-dependant manner.Conclusion The IFNa-2b therapy shows adverse effects on blood system in a dose-dependant manner,and the 3MU regimen might be the first choice in the treatment.
【Fund】: 深圳市福田区科技局(FT200627)
【CateGory Index】: R512.6
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Chinese Journal Full-text Database 1 Hits
1 MA Li-na, CHEN Xin-yue, CHEN Jie, SHEN Cheng-li, WANG Jun-tao. Beijing Youan Hospial,Capialtal University of Medical Sciences, Beijing 100054, China;Efficacy, influencing factors and safety of PEG-INF alpha-2a (PEG-INF-2a) in the treatment of chronic hepatitis C:analysis of 89 patients[J];Chinese Journal of Experimental and Clinical Virology;2006-02
Chinese Journal Full-text Database 3 Hits
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Chinese Journal Full-text Database 2 Hits
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