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《Practical Preventive Medicine》 2007-02
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Analysis of Nosocomial Infection and Antibiotic Resistance of Coagulase Negative Staphylococcus in a Primary Hospital

LI Jian-fang(Department of Clinical Laboratory,Fusha Hospital,Zhongshang 528434,Guangdong,China)  
Objective The clinical distribution and antibiotic resistance of coagative negative staphylococcus(CNS) were reviewed to provide experimental basis for correct and efficient clinical antibiotic therapy.Methods CNS was isolated and cultured according to "The Regulation of General Clinical Laboratory Operation" and tested by API staph system.Disc diffusion test(K-B method) was used to study the antimicrobial resistance.Results One hundred and thirty-five strains of CNS were isolated.They were classified into 6 species of CNS with chemical technique.Staphylococcus epidermidis and staphylococcus xylosus accounted for the majority.Methocillin resistant coagulase negative staphylococcus(MRCNS) accounted for 73.3%(99/135).Vancomycin and teicoplanin were all effective to CNS.The drug sensitivity results showed that MRCNS was highly resistant to fifteen antibiotics than methocillin-sensitive coagulase negative staphylococcus(MSCNS).Conclusions Etiologic monitoring is an effective way to detect and control the infection of CNS. Clinical microbiology laboratory should pay great attention to MRCNS detection.Antimicrobial therapy should be conducted according to susceptibility test.
【CateGory Index】: R446.5
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【Citations】
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【Co-citations】
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1 PENG Lan, CHEN Xiao-jin(Medical Center of Xingshan County, Xingshan 443711, Hubei, China);Drug Resistance Status of Staphylococcus in Montane Hospital[A];[C];2004
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