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《Practical Preventive Medicine》 2007-02
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Relationship Between Insulin Resistance and Reproduction Hormone Level,Risk of Cardiovascular Disease in Women With Polycystic Ovary Syndrome

XIONG Wen-qin1,ZHANG Wen-quan2(1.Department of Clinical Laboratory, the First Traditional Chinese Medicine Hospital of Changde City;2.Reproductive Medical Center,the First People's Hospital of Changde City,Changde 415003, Hunan)  
Objective To explore the relationship between insulin resistance(IR) and reproduction hormone level,risk of cardiovascular disease(CVD) in women with polycystic ovary syndrome(PCOS).Methods Fifty women with PCOS included 28 associated with IR and 22 without,and 30 normal women served as the controls. Serum reproductive hormones(LH,FSH,E2,PRL,and T),total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),ApoA1,ApoB and high sensitive C-reactive protein were assessed and evaluated respectively.ResultThere were highly significant differences in T,LH,TG,HDL-C,ApoA1,ApoB,and hs-CRP among these groups.Conclusion IR plays a key role in abnormal reproductive hormones levels and also increases the risk of VCD in patients with PCOS.
【CateGory Index】: R711.75;R587
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