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《Practical Preventive Medicine》 2007-02
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Clinical Observation of Carboprost Suppository in Reducing Postpartum Hemorrhage After Cesarean in High Risk Pregnancy

LIU Xu-hui(Department of Obstetrics and Gynecology,Lengshuijiang Municipal People's Hospital,Lengshuijiang 417500,Hunan)  
Objective To investigate the effect of carboprost suppository in reducing the postpartum hemorrhage after cesarean birth among high risk pregnancy. Methods Altogether 153 high risk pregnancy women accepted cesarean delivery were randomly divided into three groups: the group of taking carboprost suppository sublingually,the group of taking misoprostol sublingually and the group of injecting oxytocin intravenously.The medicine was taken immediately after child delivery and the amount of bleeding during operation,2 hours after operation and 2~24 hours after operation was compared respectively.Results During the operation and 2 hours after operation the hemorrhage quantity of the carboprost suppository group was reduced significantly and the incidence of postpartum hemorrhage was significantly less than the group injected oxytocin(P0.05).The hemorrhage quantity of the carboprost suppository group during operation was reduced significantly than that of the misoprostol group(P0.05),while there was no significant difference between the two groups 2 hours after the operation(P0.05).The blood pressure fluctuation was slight,the side effect was few and anus vent recovered quickly after taking carboprost suppository sublingually.Conclusion Taking carboprost suppository sublingually can significantly reduce hemorrhage after cesarean delivery among high risk pregnancy,and with the advantages of convenient administration,safety and reliability.
【CateGory Index】: R719.8
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