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《Practical Preventive Medicine》 2007-02
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Clinical Significance of Serum LDH and HBDH in Acute Leukemia

CAO Zhi-Hong,ZHU Yan,PENG Min-yuan(Department of Clinical Laboratory,Xiangya Hospital,Central South University,Changsha 410008 China)  
Objective To detect the changes of serum LDH and HBDH,and to study the relation between serum LDH,HBDH and the cells of leukemia and its clinical significance in patients with acute leukemia.Methods Speed ratios of serum LDH and HBDH in 70 cases of leukemic leukemia,24 cases of aleukemic leukemia and 50 cases of healthy group were assessed and analyzed.The difference of serum LDH and HBDH before and after remission were monitored.Results Serum LDH and HBDH in patients with leukemic leukemia was significantly higher than those of patients with aleukemic leukemia and healthy subjects(P0.01),but the levels of serum LDH and HBDH between aleukemic leukemia group and the control group showed no significant difference(P0.05),and the levels of serum LDH and HBDH before and after remission were significantly different(P0.01).Conclusion Serum LDH and HBDH of acute leukemia shows positive correlation with leukemia cells,and hence serum LDH and HBDH may be used as a complementary marker in diagnosis,prognosis and evaluation of treatment efficacy in acute leukemia.
【CateGory Index】: R733.7
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