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《Practical Preventive Medicine》 2007-02
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Analysis of Infections After Tumor Surgery of Oral and Maxillofacial Region and its Prevention and Cure

BAO Rong-hua,CHEN Jie,YU Jian-jun (Hunan Provicial Tumor Hospital,Changsha 410006,China)  
Objective To discuss the pathogenic species of infection after tumor surgery of oral and maxillofacial region and to explore the prevention and cure countermeasures.Methods The risk factors,pathogenic species and drug resistance of infections after oral and maxillofacial region tumor surgery were studied. Results The infection rate was 12.60%(81/643) after surgical removal of tumors in the oral and maxillofacial region.The infections were related to patient's age,invasive procedures,immobilization and aspiration.The main infected sites were the surgical wound and the lower respiratory tract.The leading pathogen was Staphyloccus(46.88%),and followed by Streptococcus(11.72%),Escherichia coli(11.72%) and Pseudomonas aeruginosa(10.94%).The fungal infection rate was 6.25%;Amoxacillin resistance staphylococcus was 66.3%,which resisted 7 antibiotics and the rate was over 50%.The Gram negative bacilli resisted 4 or more antibiotics,and the resistance rate was over 40%,there were relatively high resistance rates(55%)against most of antibiotics.There showed statistical difference between the resistant strains and the non-resistant strains. Conclusions Though Gram negative bacilli play an important role,most infections are still caused by Gram positive coccus after tumor surgrey in the oral and maxillofacial region.The antibiotics resistance rate of all bacteria pathogens rises gradually,and shows strong and multiple drug resistance. Preventive antibiotics significantly reduce the postoperative infection, and moreover,careful and skilled nursing is also the important countermeasure.
【CateGory Index】: R739.8
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