Relationship between Different Pronuclear Patterns and Potential of Embryo Development and Pregnancy
Zhong-mei LI, Yu-bao WANG, Dun-yu GU, Xiao-yun WU, De-qi JIANG, Zhen LU, Zuan-chong FENG (Infertility and IVF Center of Shanghai Institute of Planned Parenthood Research, Shanghai, 200032)
Objective: To explore the relationship between the patterns of pronucleus and embryo development and pregnancy potential in the pronuclear stage. Methods:According to the number and distribution of nu-cleolar precursor bodies, the embryos at pronuclear stage were classified into 6 pronuclear patterns from 0 to 5, 16-18 h after in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). For each pattern, the subsequent embryonic morphology and the pregnancy rate were analyzed. Results: Embryos of Pattern 0 developed to significantly more embryos with good quality and higher pregnancy potential than the embryos developing from other patterns (83.14% and 76. 11% respectively, P0. 05). The pregnancy rate was decreased as less embryos of Pattern 0 were transferred . The pregnancy rate of the groups of only Pattern 0, with Pattern 0, and without Pattern 0 were 48. 08%, 32. 14% and 21. 28% respectively (P0. 05). Conclusion: The pronuclear patterns are of the predictive value of embryo development and pregnancy potential, which can be used as a new tool for the selection of embryos in IVF and ICSI.
【CateGory Index】： R321