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《Journal of Tianjin Normal University(Natural Science Edition)》 2018-05
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Overview of DNA sequencing techniques and corresponding assembly algorithms

LI Yanhui;ZHANG Shaoqiang;College of Computer and Information Engineering,Tianjin Normal University;  
DNA sequencing techniques have been around for four generations. A general overview of the four-generation DNA sequencing techniques and their related reads assembly algorithms are presented. The characteristics of each genera-tion of sequencing techniques are introduced,and the main ideas and characteristics of related read assembly algorithms are analyzed in detail through comparing the four-generation sequencing techniques. Finally,the challenges of the cur-rent assembly algorithms are analyzed,and the new research directions are pointed out.
【Fund】: 国家自然科学基金资助项目(61572358);; 天津市自然科学基金资助项目(16JCYBJC23600)
【CateGory Index】: TP301.6
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