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Prediction and Prevention of OHSS in the Cycles of Induction of Superovulation

Jin Lei; Luo Lilan; Zhu Guijin (Department of Obstetrics and cynecology,Tongji Hospital,Tongji Medical University,Wuhan 430030)  
There were 5/16 patients with OHSS (4 mild to moderate cases and 1 severe case) in the cycles of induction of superovulation for GIFT procedures. The incidences of common OHSS and severe OHSS were 31. 3 % and 6.3%, respectively. No significant difference was found in age and etiology of infertility between the patients with and without OHSS (P0.05). The dosages of hMG and hCG given in luteal phase for OHSS were signsificantly higher than for non OHSS (P0.05). E2 level and number of follicles of these two groups were significantly different (P0.05). The incidence of OHSS in pregnancy cycles was 5 fold than in nonpregnancy cycles (57% and 11%). Our result showed that the incidence of OHSS was closely associated with dosage of hMG/hCG. E2 level≥1 500 ng/L and number of follicles≥10 are the high risk factors of OHSS, and it is also more frequently seen in pregnant cycles. Carefully monitoring during hMG induction by transvaginal sonography and serum E2 assay can effectively prevent OHSS.
【Fund】: 湖北省科委资助!No.90J57
【CateGory Index】: R442.8
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