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《Progress In Microbiology and Immunology》 2001-01
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Immune effect of hemaglutinin(HA)gene and Neuraminidase(NA)gene of Influenza virus

ZHOU Xu,LI Yi min,HOU Ling,et al (Lanzhou Institute of Biological Products,Lanzhou 730046)  
Applying HA gene of and NA gene influenza virus to immunize BALB/c mice,the apparent specific reaction was observed.The titer of antibody was shown a positive correlation with the amount of applied genes.The livability of immunized mice were 100%,after challenging with the same type of influenza virus in each tested group.The livability of HA gene immunized mice were 100%,challenging with hetero type of the virus.The livability of NA gene immunized mice were 75%,challenging with hetero type of the virus.The mice were attacked by hetero type of the virus,which were immunized by the combination of HA gene and NA gene,their livability were 100%.
【Fund】: 甘肃省自然科学基金资助项目! (ZS991 A2 3 0 6 6 Y)
【CateGory Index】: R392.3
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