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《Progress In Microbiology and Immunology》 2003-01
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Initial study of interaction on intestinal microfold cell in mice with two enteroinvasive bacterium

CHEN Jie, PENG Hong, WANG Hua, et al. (Department of Immunology, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences,Beijing,100071)  
By using murine intestinal loop to be locally infected, observations were made at different infection time and detection of cell apoptosis occured on follicular-associated epithelium(FAE) on the surface of Peyer's patch. The results showed that Salmonella 460043 and Shigella F 2a-12 attached on the surface of microfold cells (M cells) after local infection for 30 min, both invaded into M cells as well as lymphocytes after local infection for 60-90 min. The ration of cell apoptosis was most significant in comparison with the control after infection for 6~8 h. It indicated that the two strains passed the epithelial barrier by entering M cells result in local mucosal respone.
【Fund】: 国家自然科学基金资助项目 (No .39970 0 42 )
【CateGory Index】: R392
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【References】
Chinese Journal Full-text Database 1 Hits
1 Zhu Yu,Jiang Hong,Xia Jialing,et al.West China Second Hospital,Sichuan University,Chengdu,Sichuan 610041,China;Expression of Tumorous Necrosis Factor-alpha in Several Models of Salmonella Typhimurium Infected Mice[J];Sichuan Medical Journal;2007-01
【Co-references】
Chinese Journal Full-text Database 2 Hits
1 Xu Yao,Bian Guowu, Yang Jieren Depanment of Pharmacology, Depanment of Microbiology and Immunology, Wannan Medical College, Anhui Province 241001;Immunomodulatory effects of Liu Wei Di Huan Tang on hydrocortisone model mice[J];;2000-13
2 LI Tiemin,XU Hao (Department of Life Science,Liaoning University,Shenyang 110036);Response of human mononuclear Phagocytes to Salmonella typhimurium in vitro[J];Chinese Journal of Zoonoses;2003-01
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