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《Journal of Hygiene Research》 2002-04
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Study on the effects of cooking oil fume condensate on the DNA integrality

Zhang Hui, Wang Guoxiong, Tan Weijun Department of Environmental Health, College of Public Health, Southeast University, Nanjing 210009, China  
The aim of this study was to study the DNA damage mechanisms of cooking oil fumes (COF) in vitro. The colorimetric MTT reduction assay was adopted to measure the effects of the cytotoxicity of COF condensate on typeⅡpneumocytes from the lungs in the rats. The condensate of COF was of the dose-responsive effect on cell-inhibit rate to some extent (r=0.943, P0.01). There is distinctive cytotoxicity on typeⅡpneumocytes when concentration is higher than 20μg /ml. The genotoxicities of COF condensate to typeⅡpneumocytes were studied by modified alkaline single-cell gel using a electrophoresis(SCGE) assay(comet assay), the maximum concentration of condensate is below the concentration of cytotoxicity. The results showed that the condensate of COF was of the dose-responsive effect on the typeⅡpneumocytes DNA damage to some extent(r=0.918,P0.05) at the dosage of 0-5μg/ml. The DNA damage reach to the maximum at the dosage of 10μg/ml. The damaged DNA could be restored after been cultured for 2 hours. Calf thymus DNA cross-link after the administration of COF condensate were measured with ethidium bromide assay. It was found that condensate of COF was of the dose-responsive effect on the calf thymus DNA cross-links to some extent(r=0.963,P0.01). The above results suggested that cooking oil fume condensate could induce DNA damage at much lower dosage and result in the increase of DNA cross-links in a certain concentration.
【CateGory Index】: R99
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Chinese Journal Full-text Database 2 Hits
1 ZHENG Lianying,MIAO Jianyu and GUO Xiaofen (Department of Chemical and Biochemical Engineering,Zhejiang University,Hangzhou 310027,Zhejiang,China);SCREENING OF OILY SMOKE DEGRADING BACTERIA AND THEIR DEGRADATION POWER[J];Journal of Chemical Industry and Engineering(China);2004-05
2 Xu Zhen,Jin Yinlong Institute for Environmental and Health Related Product Safety, China Center for Disease and Prevention, Beijing 100021,China;Main indoor air pollutants and their health impacts[J];Journal of Hygiene Research;2003-03
Chinese Journal Full-text Database 4 Hits
1 Meng Ziqiang 1\ and Zhang Lianzhen 2 1\ Division of Environmental Biological Toxicology and Department of Life sciences, Shanxi University, Taiyuan 030006\ 2 China Institute for Radiation Protection, Taiyuan 030006;PRINCIPLE AND METHOD OF THE SINGLE CELL MICROGEL ELECTOPHORESIS (SCGE) TECHNIQUE TO STUDY DNA DAMAGE IN MAMMALIAN CELLS[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1998-06
2 Zheng Yongtang & Ben Kunlong (Kunming Institute of Zooloy,Academia Sinica, Kunming 650107);Use of MTT Assay for the Determination of Cell Viability and Proliferation[J];Immunological Journal;1992-04
3 Wang Kaixiong Zhu Xingdong (Zhejiang University, Hangzhou 310029);The Constituents in Cooking-Oil Smoke and their Analytical of Methods[J];Shanghai Environmental Sciences;1999-11
4 Li Shuguang, Wang Yunxiang, Zhang Jing, Zhao Xiansi, et al. Shanghai Tiedao University Medical College,Shanghai 200070,China;Study on the chemical components of edible oil fume in kitchen and its genotoxity on Drosophila[J];JOURNAL OF HYGIENE RESEARCH;1999-01
Chinese Journal Full-text Database 10 Hits
1 LUO Peng+1, ZHANG Ai-hua+1, LI Jun+1, QING Du-cai+2, REN Yu-jiang+1, ZHAGN Bi-xia+2, WANG Xi-lan+1, HUANG Xiao-xing+2(1. Dept. of Preventive Medicine, Guiyang Medical College, Guiyang 550004, China; 2. 44th Hospital of PLA, Guiyang 550009, China);INHIBITORY EFFECT OF LITHIUM CARBONATE ON GENETIC AND OXIDATIVE DAMAGE IN CANCER PATIENTS WITH RADIOTHERAPY AND CHEMOTHERAPY[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-02
2 ZONG Chu an-long, ZOU B ai-yun, LIU J ing-sheng, et al(Biology Department of Taishan Medical College,Taian 271000,China);ANTAGONISTIC ACTION OF GARLIC EXTRACT AND VITAMIN E TO MUTAGENIC ITY OF COOKING OIL FUMES[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-03
3 ZHANG Qiao-xin, LUO Wen-hong ,LI Hui, et al( The Center Laboratory of Shantou University Medical College,Shantou 515031,China);INVESTIGATION ON DNA DAMAGE OF HUMAN LYMPHOCYTES BY H_2O_2 WITH COMET ASSAY AND OBSERVATION OF THE COMET'S 3-D STRUCTURE BY CONFOCAL MICROSCOPE[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-04
4 LIU Xiu-fang 1 ,HE Li-ping 1 ,HU Shang-ping 2 ,GUO Feng-ying 2 (1.Department of Hygienic Toxicology,Ningxia Medical College,Yinchuan750004,Ningxia,China;2.Department of Pathomorphology,Ningxia Medical College,Yinchuan750004, Ningxia,China);Expression of P53 and P16 Proteins of Lung Tissues in Rats Exposed to Cooking Siritch Oil Fume[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-01
5 CHANG Guimin ,DUAN Fangling,ZHANG Xiangdong ,et al. Digestive Disease Research Center,The Third Hospital of Beijing Medical University,Beijing 100083,China;Experimental study on antitumor activity of neogalactolipid modified adriamycin liposome on liver cancer cells SMMC7721[J];CHINESE JOURNAL OF CANCER;1999-03
6 ZHU Ya-Hong1 YAN Hui1 GUI Zhong-Zheng1,2(1School of Biological and Environmental Engineering,Jiangsu University of Science and Technology,Zhenjiang Jiangsu 212018,China;2The Sericultural Research Institute,Chinese Academy of Agricultural Sciences,Zhenjiang Jiangsu 212018,China);A Study on the Protective Effect of Cordyceps militaris Polysaccharide to the Primary Cultured Rat Hepatocytes Injured by CCl_4[J];Science of Sericulture;2009-01
7 LIU Xing-Hua,ZHU Mei-ling,CHEN Ti,et al.Department of Ophthalmology, The First Affiliated Hospital,Anhui Medical University,Hefei 230022,China;Observation on Biological Character of Cultivated Cornea Limbal Epithelial Cells[J];Journal of Chinese Physician;2003-04
8 WANG Yi,WANG Zhen-wei(Department of Analytical Chemistry,College of Medical Laboratory,Third Military Medical University,Chongqing 400038,China);Inhibition effect on LPS-induced TNF-α release by homegrown and Australian Melaleuca alternifolia(Tea Tree)oil[J];Acta Academiae Medicinae Militaris Tertiae;2007-04
9 Xu Zengguang,et al Institute of Occupational Medicine,Tongji Medical University,Wuhan;STUDY ON ANTAGONISM OF GEFFERY TO THE TOXICITY OF FLUORIDE[J];Chinese Journal of Control of Endemic Disease;1994-03
10 Zheng Yongtang Ben Kunlong (Kunming Insitute of Zoology,Chinese Academy of Sciences,Kunming,Yunnan 650223);RIBOSOME INACTIVATING PROTEINS WITH ANTI HUMAN IMMUNODEFICIENCY VIRUS ACTIVITIES[J];EXPLORATION OF NATURE;1997-02
China Proceedings of conference Full-text Database 1 Hits
1 Zhang Hui, Wang Guoxiong, Shen Chuanlai, Xiang Longsheng, et al. (Department of Environmental Health, Public Health School, South east University, Nanjing 210009);Investigation on the Immunological Index for Cell-mediated Immunity in Cooking Workers[A];[C];2005
Chinese Journal Full-text Database 10 Hits
1 LIU Hong mei,LIU Zhi hong,YU Wei,et al(Department of Public Health,Ningxia Medical College,Yinchuan 750004 China);Effects of Siritch Vapor Condensate on Zn,Cu,Fe and CaContents in Mice Liver[J];Industrial Health and Occupational Diseases;2003-03
2 Li Shuguang;Analysis of Polycyclic Aromatic Hydrocarbons in the Edible Oils and Its Heated Products of Some Catering Trades[J];Journal of Environment and Health;1992-05
3 Li Dongyang,Xie Hongwei,Rang Weiqing,et al.the Department of Hygiene,Hengyang Medical College,421001;Effects of Cooking Oil Fume on the Lipid Peroxidation and Levels of Zinc,Copper and Iron in Lung Tissue and Serum Among Rats During Different Exposure Periods[J];JOURNAL OF ENVIRONMENT AND HEALTH;1999-06
4 Ye Lin,Ren Shuping,Lu Yi,et al.Preventive Medical College,Norman Bethune University of Medical Sciences,Changchun 130021;Damage of Alveolar Macrophage in Rats Induced by Cooking Oil Fume[J];JOURNAL OF ENVIRONMENT AND HEALTH;1999-06
5 ZHANG Hui,WANG Guo xiong,ZHAO Li,et al Department of Environmental Health,College of Public Health,Southeast University,Nanjing 210009;Influence of Cooking Oil Fumes on Human Immune Function[J];Journal of Environment and Health;2001-03
6 Institute of Hygiene and Environmental Medicine, Academy of Military Medical Sciences,Tianjin 300050,China;Oxidative Damage of DNA and Formation of Its Biomarker 8-Hydroxydeoxyguanosine Induced by Heated Cooking Oil Vapors[J];Journal of Environment and Health;2003-05
7 Wang Lihua;et al(Dept.of Envlronmental Hyglene,Beijing Medical University100083);Relationship Between Air Pollution and Changes in Children's Peak Expiratory Flow(PEF)[J];JOURNAL OF ENVIRONMENT AND HEALTH;1994-06
8 Zhou Yamei,Zhang Zhengdong,Weng Niannong et al.Dept of Environmental Mcdicine,Nanjing Medical University,Nanjing 210029;The Effect of Cooking Oil Vapors on Lipid Peroxidation and the Fluidity of Pulmonary Alveolar Macrophage Membranes in Rats[J];JOURNAL OF ENVIRONMENT AND HEALTH;1997-02
9 Yin Lihong,Pu Yaopu,Li Yunhui,et al.Department of Envivonmental Health,Nanjing Railway Medical College,210009;The Effect of Organic Extracts of Cooking Oil Fume Particulates on Cell Circles of Type Pulmanory Cells in Rats[J];JOURNAL OF ENVIRONMENT AND HEALTH;1999-03
10 LONG Li-liang,CHEN Feng,HE Xing-peng,et al (School of Public Health ,Nanhua University,Hengyang, Hunan 421001,China);Acute Toxicity COF on Rats[J];Journal of Nanhua University(Medical Edition);2003-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 XU Lan-qin1,TAO Tao1,DENG Sui-de2,LU Jia-chun1,RAN Pi-xin3(1Department of Chemistry,Guangzhou Medical College,Guangzhou 510182,China;2Department of Laboratory Investigation,First Municipal People's Hospital,Guangzhou Medical College,Guangzhou 510180,China;3Institute of Respiratory Diseases,Guangzhou Medical College,Guangzhou 510182,China);The Impact of Aldehydes and Ketones Combustion on Anti-oxidative Capacities of Lungs in Mice[J];Academic Journal of Guangzhou Medical College;2007-03
2 QIAN Zhi-yong,MA Yong-min,XIE Yong-ling.Tianjin Medical University,Tianjin 300011,China;Effects of Volatile Organic Compounds Escaped from Alkyd Dope on Neurotransmitter Content in Brain of Mice[J];Journal of Environment and Health;2007-03
3 LI Zi-min,HE Ai-tao,WU Cheng-qiu,et al(Department of Hygiene,School of Public Health,Nanhua University,Hengyang,Hunan 421001,China);The Utilization of Mouse Forelimb Buds Culture for Evaluating the Developmental Toxicity of Benzene in Vitro[J];Journal of Nanhua University(Medical Edition);2007-02
4 WANG Ye-jing SU Fei CHENG Cai-yun XU Ning ZHANG Lin-ying ZHAO Zhi-qiang SHU Wei-ping Huangpu District Center for Disease Prevention and Control,Shanghai 200011,China;Assessment on the Factors Harmful to Health in Public Internet Café[J];Journal of Environmental & Occupational Medicine;2007-04
5 LI Yong,LI Chun-ying,YANG Shuang-bo,et al(School of Public Health,University of South China,Hengyang,Hunan 421001,China);The Developmental Toxicity Effect of Benzene on Mouse Embryo in Vivo[J];Journal of University of South China(Medical Edition);2009-03
6 WANG Xiu-ying, YU Shu-yuan, NIU En-hong, KANG Li(Shenzhen Center for Disease Control and Prevention, Shenzhen 518020, China);Effect of Volatile Organic Compounds in Indoor Renovation on the DNA Damage in Peripheral Blood Lymphocytes in Human and Mice[J];Journal of Tropical Medicine;2006-07
7 JIANG Jie1,MAO Ting1,LU Yong1,WU Ying2,FENG Li-ping1(1.Beijing Municipal Center for Food Safety Monitoring,Beijing 100041,China;2.Beijing Products Quality Supervision and Inspection Institute,Beijing 100029,China);Multivariate Optimization and HS/GC-MS Analysis of Benzne,Toluene and Xylenes in Waterbased Adhesives[J];Journal of Instrumental Analysis;2009-09
8 LI Zi-min,HE Ai-tao,WU Cheng-qiu,et al.School of Public Heath,Nanhua University(Hengyang 421001,China);Developmental toxicity effect of benzene on embryo mouse forelimb buds[J];Chinese Journal of Public Health;2008-04
9 LIAO Lei1,2*,QIAN Gong-wang1(1.State Key Laboratory of Pulp and Paper Engineering,South China University of Technology,Guangzhou 510640,China;2.Department of Resources and Environmental Engineering,Guilin University of Technology,Guilin 541004,China).;Domestication、culturing and property of the dominant bacterial strains degrading pollutants from cooking fume.[J];China Environmental Science;2006-06
10 CAI Xiu-cheng,NI Ya-jie,YU Ming-yue,et al.Jilin Provincial Center for Disease Control and Prevention,Changchun Jilin 130062,China;Detection and Experimental Study of the Indoor Air Quality in Newly Decorated Houses of Changchun[J];Chinese Journal of Public Health Engineering;2007-05
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Meng Ziqiang Department of Environmental Sciences, Shanxi University, Taiyuan;RADIATION-INDUCED DNA SINGLE STRAND BREAKS AND THEIR REJOINING IN MAMMALIAN CELLS BY HYDROXYLAPATITE CHROMATOGRAPHY[J];Journal of Radiation Research and Radiation Processing;1987-04
2 Liu Guangming; Wang Kaixiong; Chen Xiaoyan(Environmental Science Department of Zhejiang Agricultural University , Hangzhou 310029);Monitoring of Oil-smoke Discharge from Restaurants by Gravity Method[J];ENVIRONMENTAL POLLUTION & CONTROL;1997-04
3 Liu Guangming,Wang Kaixiong, Zang Rongchun, Environmental Protection Department, Zhejiang Agricultural University, Hangzhou 310029;The fluorometric determination of aldehydes in restaurants' oil smoke[J];Environmental Pollution & Control;1998-04
4 Meng Ziqiang (Department of Environmental Sciences,Shanxi University,Taiyuan) Zhang Lianzheng (Institute for Radiation Protection,MNI);A METHOD FOR DETERMINATION OF STRAND SEPARATION RATE OF DNA IN ALKALI AND ITS USE INDNA DAMAGE STUDY[J];Acta Scientiae Circumstantiae;1988-01
6 Li Shuguang;Analysis of Polycyclic Aromatic Hydrocarbons in the Edible Oils and Its Heated Products of Some Catering Trades[J];Journal of Environment and Health;1992-05
7 Zhou Yamei ( Naijing Medical University, Naijing 210029 );Health Effects of Cooking Oil Fume[J];Shanghai Environmental Sciences;1997-02
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