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Mcl-1 gene and its role in leukemia

JI Xiaoxia,TAN Hui,SU Qi (Cancer Research Institute,University of South China,Hengyang Hunan 421001,China)  
Mcl-1,as a member of Bcl-2 family plays an important role in the cell survival,apoptosis,cell cycle and differentiation.Mcl-1 gene closely related to the development of the malignancy of hematological system.Now we reviewed the structure and function of Mcl-1 and its role in leukemia.
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