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《International Journal of Pathology and Clinical Medicine》 2009-04
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Signal transduction of epithelial-mesenchymal transition

REN Chen,SHEN Hong (Department of Pathology,Southern Medical University,Guangzhou 510515,China)  
Epithelial-mesenchymal transition (EMT) occurs under various physiological and pathological conditions,such as in the development of embryo and organ,in the formation and transfer of tumor,and in the process of fibrosis,TGF-β is an important induced factor that regulates the EMT genesis through Smad-dependent and non-Smad pathway.It plays a key role in the formation,transfer and diffusion of tumor.This paper reviews the research progress on EMT in recent years.
【CateGory Index】: R730.2
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