Full-Text Search:
Home|About CNKI|User Service|中文
Add to Favorite Get Latest Update

Angiogenesis and the regulation mechanism in glioma

HUANG Chunhai1,2,LI Xuejun2,YAUN Xianrui2 (1.Department of Neurosurgery,First Affiliated Hospital,Jishou University,Jishou Hunan 416000;2.Department of Neurosurgery,Xiangya Hospital,Central South University,Changsha 410008,China)  
Studies in vitro show that the growth of solid tumor is vessel dependent.Solid tumor usually stops growing when its diameter is over 2 mm due to lack of new vessel to supply blood.Glioma is one of the most malignant tumor in vascularization.As a solid tumor,the vascularization in glioma also includes vasculogenesis and angiogenesis.Vasculogenesis is defined as the differentiation of precursor cells(angioblasts) into endothelial cells and the de novo formation of a primitive vascular network,whereas angiogenesis is defined as the growth of new capillaries from pre-existing blood vessels.Angiogenesis,which plays a significant role in the development of tumor,has become a new target for the prognostic evaluation and therapy of glioma.Recently,the research in exploring the mechanism of angiogenesis has attracted great attention.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©CNKI All Rights Reserved